Individual Study / WHI

Women's Health Initiative

Women's Health Initiative

WHI logo
Initiatives -
Start Year
End Year
National Heart, Lung, and Blood Institute and NHLBI
Supplementary Information
Visit WHI


Investigators Contacts
  • Dr. Garnet Anderson
    Public Health Sciences Division, Fred Hutch
  • Dr. Prof. Sally A. Shumaker
    Wake Forest School of Medicine


Study design
Other : Clinical Trial; Observational study
Follow Up
Women in the clinical trial are followed through regularly scheduled examinations to ensure the timely ascertainment of updated medical histories, tomonitor the occurrence of possible adverse effects, to dispense study medications, and to promote adherence to the study protocol. Observational study (OS) participants are contacted annually by mail to obtain updates of their medical histories and selected exposure data. At about 3 years after enrollment, all OS participants are invited to a clinic follow-up visit to update selected baseline data, to obtain additional risk factor data, and to collect a blood specimen.
Supplementary Information

Marker Paper

Design of the Women's Health Initiative clinical trial and observational study. The Women's Health Initiative Study Group. Control Clin Trials. 1998 Feb;19(1):61-109. doi: 10.1016/s0197-2456(97)00078-0.

PUBMED 9492970


Sources of Recruitment
  • Individuals

Number of participants

Number of participants
Number of participants with biosamples
Supplementary Information
Post-menopausal women. The average age of women still active in WHI is 83 years and ranges from 71 to 103 years.


Availability of data and biosamples


Availability of access information

On the study website :