Individual Study / VDAART

Vitamin D Antenatal Asthma Reduction Trial (VDAART)

Vitamin D Antenatal Asthma Reduction Trial (VDAART)

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Initiatives -
We will first determine the patterns of change in the early intestinal microbiome (both composition and metabolic function) up to age 6 years old that are related with vitamin D deficiency in the prenatal and perinatal periods. We will also investigate genetic markers of the host that affect these patterns in the intestinal microbiome. We will then investigate the relationship of these patterns of change in the microbiome with the presence of asthma by age 6 year.
Start Year
2016
End Year
2023
Funding
National Institutes of Health (NIH)
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Members

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Investigators Contacts
  • MD. Prof. Scott Weiss
    Brigham and Women's Hospital and Harvard Medical School

Design

Study design
Population cohort

Marker Paper

Lee-Sarwar KA, Lasky-Su J, Kelly RS, Litonjua AA, Weiss ST. Gut Microbial-Derived Metabolomics of Asthma. Metabolites. 2020 Mar 6;10(3):97. doi: 10.3390/metabo10030097.

PUBMED 3215596

Recruitment

Sources of Recruitment
  • Individuals

Number of participants

Number of participants
Number of participants with biosamples

Access

Availability of data and biosamples

Data
Biosamples
Other