Vitamin C to Decrease Effects of Smoking in Pregnancy on Infant Lung Function
Initiatives
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The purpose of this ECHO application is to combine the offspring from the prenatal cohorts of two RCTs studying the effects of vitamin C supplementation(500 mg per day) to pregnant smokers on offspring respiratory outcomes and to determine if the innovative therapy of maternal vitamin C supplementation during pregnancy leads to prolonged improvements on offspring’s pulmonary function tests (PFTs) and respiratory health.
- Start Year
- 2007
- End Year
- 2023
Visit VCSIP
| Investigators | Contacts |
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Design
- Study design
- Clinical trial cohort
Marker Paper
McEvoy CT, Shorey-Kendrick LE, Milner K, Schilling D, Tiller C, Vuylsteke B, Scherman A, Jackson K, Haas DM, Harris J, Schuff R, Park BS, Vu A, Kraemer DF, Mitchell J, Metz J, Gonzales D, Bunten C, Spindel ER, Tepper RS, Morris CD. Oral Vitamin C (500 mg/d) to Pregnant Smokers Improves Infant Airway Function at 3 Months (VCSIP). A Randomized Trial. Am J Respir Crit Care Med. 2019 May 1;199(9):1139-1147. doi: 10.1164/rccm.201805-1011OC.
PUBMED 30522343
Recruitment
- Sources of Recruitment
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- Families
Number of participants
- Number of participants
- 252
- Number of participants with biosamples
Access
Availability of data and biosamples
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| Biosamples | |
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