Synchros | TOSS

Twin Offspring Study in Sweden

Initiatives -

Funding: National Institutes of Health
Supplementary Information: IGEMS (17) (Interplay of Genes and Environment across Multiple Studies)

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Members

Investigators	Contacts
Dr. Professor Paul Lichtenstein Karolinska Institutet Paul Lichtenstein Title Dr. Professor Name Paul Lichtenstein Email paul.lichtenstein@ki.se Institution Karolinska Institutet

Design

Study design: Population cohort
Follow Up: 3 waves.

Marker Paper

Clausson B, Lichtenstein P, Cnattingius S. Genetic influence on birthweight and gestational length determined by studies in offspring of twins. BJOG. 2000;107(3):375-381. doi:10.1111/j.1471-0528.2000.tb13234.x

PUBMED 10740335

Recruitment

Sources of Recruitment

Individuals
Families

Number of participants

Number of participants: 3,000
Number of participants with biosamples
Supplementary Information: This project extends the Twin Moms Project and includes a sample of twin fathers and their families (N=320 twin pairs and their families) and to collect an addition 250 pairs of twin mothers for a sample of 900 twin parents and their families (total N about 3,000 individuals). Born in Sweden before 1959, who both delivered single births from 1973–1993.

Access

General Information

Availability of data and biosamples

Data
Biosamples
Other

Availability of access information

By contacting the study representative

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[in template "libs/study.ftl" in macro "studyAccessInfo" at line 597, column 35] - Reached through: @studyAccessInfo study=study [in template "libs/study.ftl" in macro "studyAccess" at line 334, column 17] - Reached through: @studyAccess study=study [in template "libs/study.ftl" in macro "studyModel" at line 28, column 11] - Reached through: @studyModel study=study type=type [in template "study.ftl" at line 189, column 9] ---- Java stack trace (for programmers): ---- freemarker.core.InvalidReferenceException: [... Exception message was already printed; see it above ...] at freemarker.core.InvalidReferenceException.getInstance(InvalidReferenceException.java:134) at freemarker.core.UnexpectedTypeException.newDescriptionBuilder(UnexpectedTypeException.java:85) at freemarker.core.UnexpectedTypeException.(UnexpectedTypeException.java:48) at freemarker.core.NonHashException.(NonHashException.java:49) at freemarker.core.Dot._eval(Dot.java:48) at freemarker.core.Expression.eval(Expression.java:101) at freemarker.core.DefaultToExpression._eval(DefaultToExpression.java:88) at freemarker.core.Expression.eval(Expression.java:101) at freemarker.core.DollarVariable.calculateInterpolatedStringOrMarkup(DollarVariable.java:100) at freemarker.core.DollarVariable.accept(DollarVariable.java:63) at freemarker.core.Environment.visit(Environment.java:331) at freemarker.core.Environment.visit(Environment.java:337) at freemarker.core.Environment.visit(Environment.java:373) at freemarker.core.Environment.invokeMacroOrFunctionCommonPart(Environment.java:872) at freemarker.core.Environment.invokeMacro(Environment.java:809) at freemarker.core.UnifiedCall.accept(UnifiedCall.java:83) at freemarker.core.Environment.visit(Environment.java:331) at freemarker.core.Environment.visit(Environment.java:373) at freemarker.core.Environment.invokeMacroOrFunctionCommonPart(Environment.java:872) at freemarker.core.Environment.invokeMacro(Environment.java:809) at freemarker.core.UnifiedCall.accept(UnifiedCall.java:83) at freemarker.core.Environment.visit(Environment.java:331) at freemarker.core.Environment.visit(Environment.java:337) at freemarker.core.Environment.visit(Environment.java:373) at freemarker.core.Environment.invokeMacroOrFunctionCommonPart(Environment.java:872) at freemarker.core.Environment.invokeMacro(Environment.java:809) at freemarker.core.UnifiedCall.accept(UnifiedCall.java:83) at freemarker.core.Environment.visit(Environment.java:331) at freemarker.core.Environment.visit(Environment.java:337) at freemarker.core.Environment.process(Environment.java:310) at freemarker.template.Template.process(Template.java:383) at org.springframework.web.servlet.view.freemarker.FreeMarkerView.processTemplate(FreeMarkerView.java:368) at org.springframework.web.servlet.view.freemarker.FreeMarkerView.doRender(FreeMarkerView.java:285) at org.springframework.web.servlet.view.freemarker.FreeMarkerView.renderMergedTemplateModel(FreeMarkerView.java:235) at org.springframework.web.servlet.view.AbstractTemplateView.renderMergedOutputModel(AbstractTemplateView.java:167) at org.springframework.web.servlet.view.AbstractView.render(AbstractView.java:304) at org.springframework.web.servlet.DispatcherServlet.render(DispatcherServlet.java:1286) at org.springframework.web.servlet.DispatcherServlet.processDispatchResult(DispatcherServlet.java:1041) at org.springframework.web.servlet.DispatcherServlet.doDispatch(DispatcherServlet.java:984) at org.springframework.web.servlet.DispatcherServlet.doService(DispatcherServlet.java:901) at org.springframework.web.servlet.FrameworkServlet.processRequest(FrameworkServlet.java:970) at org.springframework.web.servlet.FrameworkServlet.doGet(FrameworkServlet.java:861) at javax.servlet.http.HttpServlet.service(HttpServlet.java:687) at org.springframework.web.servlet.FrameworkServlet.service(FrameworkServlet.java:846) at javax.servlet.http.HttpServlet.service(HttpServlet.java:790) at org.eclipse.jetty.servlet.ServletHolder.handle(ServletHolder.java:799) at org.eclipse.jetty.servlet.ServletHandler$ChainEnd.doFilter(ServletHandler.java:1631) at org.obiba.mica.web.filter.ClickjackingHttpHeadersFilter.doFilter(ClickjackingHttpHeadersFilter.java:41) at org.eclipse.jetty.servlet.FilterHolder.doFilter(FilterHolder.java:193) at org.eclipse.jetty.servlet.ServletHandler$Chain.doFilter(ServletHandler.java:1601) at com.codahale.metrics.servlet.AbstractInstrumentedFilter.doFilter(AbstractInstrumentedFilter.java:97) at org.eclipse.jetty.servlet.FilterHolder.doFilter(FilterHolder.java:193) at org.eclipse.jetty.servlet.ServletHandler$Chain.doFilter(ServletHandler.java:1601) at org.obiba.mica.config.WebConfiguration$NoTraceFilter.doFilter(WebConfiguration.java:298) at org.eclipse.jetty.servlet.FilterHolder.doFilter(FilterHolder.java:193) at org.eclipse.jetty.servlet.ServletHandler$Chain.doFilter(ServletHandler.java:1601) at org.eclipse.jetty.websocket.server.WebSocketUpgradeFilter.doFilter(WebSocketUpgradeFilter.java:228) at org.eclipse.jetty.servlet.FilterHolder.doFilter(FilterHolder.java:193) at org.eclipse.jetty.servlet.ServletHandler$Chain.doFilter(ServletHandler.java:1601) at org.obiba.shiro.web.filter.AuthenticationFilter.doFilterInternal(AuthenticationFilter.java:158) at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107) at org.eclipse.jetty.servlet.FilterHolder.doFilter(FilterHolder.java:193) at org.eclipse.jetty.servlet.ServletHandler$Chain.doFilter(ServletHandler.java:1601) at org.springframework.web.filter.RequestContextFilter.doFilterInternal(RequestContextFilter.java:99) at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107) at org.eclipse.jetty.servlet.FilterHolder.doFilter(FilterHolder.java:193) at org.eclipse.jetty.servlet.ServletHandler$Chain.doFilter(ServletHandler.java:1601) at org.springframework.web.filter.HttpPutFormContentFilter.doFilterInternal(HttpPutFormContentFilter.java:109) at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107) at org.eclipse.jetty.servlet.FilterHolder.doFilter(FilterHolder.java:193) at org.eclipse.jetty.servlet.ServletHandler$Chain.doFilter(ServletHandler.java:1601) at org.springframework.web.filter.HiddenHttpMethodFilter.doFilterInternal(HiddenHttpMethodFilter.java:93) at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107) at org.eclipse.jetty.servlet.FilterHolder.doFilter(FilterHolder.java:193) at org.eclipse.jetty.servlet.ServletHandler$Chain.doFilter(ServletHandler.java:1601) at org.springframework.web.filter.CharacterEncodingFilter.doFilterInternal(CharacterEncodingFilter.java:197) at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107) at org.eclipse.jetty.servlet.FilterHolder.doFilter(FilterHolder.java:193) at org.eclipse.jetty.servlet.ServletHandler$Chain.doFilter(ServletHandler.java:1601) at org.eclipse.jetty.servlet.ServletHandler.doHandle(ServletHandler.java:548) at org.eclipse.jetty.server.handler.ScopedHandler.handle(ScopedHandler.java:143) at org.eclipse.jetty.security.SecurityHandler.handle(SecurityHandler.java:600) at org.eclipse.jetty.server.handler.HandlerWrapper.handle(HandlerWrapper.java:127) at org.eclipse.jetty.server.handler.ScopedHandler.nextHandle(ScopedHandler.java:235) at org.eclipse.jetty.server.session.SessionHandler.doHandle(SessionHandler.java:1624) at org.eclipse.jetty.server.handler.ScopedHandler.nextHandle(ScopedHandler.java:233) at org.eclipse.jetty.server.handler.ContextHandler.doHandle(ContextHandler.java:1434) at org.eclipse.jetty.server.handler.ScopedHandler.nextScope(ScopedHandler.java:188) at org.eclipse.jetty.servlet.ServletHandler.doScope(ServletHandler.java:501) at org.eclipse.jetty.server.session.SessionHandler.doScope(SessionHandler.java:1594) at org.eclipse.jetty.server.handler.ScopedHandler.nextScope(ScopedHandler.java:186) at org.eclipse.jetty.server.handler.ContextHandler.doScope(ContextHandler.java:1349) at org.eclipse.jetty.server.handler.ScopedHandler.handle(ScopedHandler.java:141) at org.eclipse.jetty.server.handler.gzip.GzipHandler.handle(GzipHandler.java:763) at org.eclipse.jetty.server.handler.HandlerWrapper.handle(HandlerWrapper.java:127) at org.eclipse.jetty.server.Server.handle(Server.java:516) at org.eclipse.jetty.server.HttpChannel.lambda$handle$1(HttpChannel.java:400) at org.eclipse.jetty.server.HttpChannel.dispatch(HttpChannel.java:645) at org.eclipse.jetty.server.HttpChannel.handle(HttpChannel.java:392) at org.eclipse.jetty.server.HttpConnection.onFillable(HttpConnection.java:277) at org.eclipse.jetty.io.AbstractConnection$ReadCallback.succeeded(AbstractConnection.java:311) at org.eclipse.jetty.io.FillInterest.fillable(FillInterest.java:105) at org.eclipse.jetty.io.ChannelEndPoint$1.run(ChannelEndPoint.java:104) at org.eclipse.jetty.util.thread.strategy.EatWhatYouKill.runTask(EatWhatYouKill.java:338) at org.eclipse.jetty.util.thread.strategy.EatWhatYouKill.doProduce(EatWhatYouKill.java:315) at org.eclipse.jetty.util.thread.strategy.EatWhatYouKill.tryProduce(EatWhatYouKill.java:173) at org.eclipse.jetty.util.thread.strategy.EatWhatYouKill.run(EatWhatYouKill.java:131) at org.eclipse.jetty.util.thread.ReservedThreadExecutor$ReservedThread.run(ReservedThreadExecutor.java:409) at org.eclipse.jetty.util.thread.QueuedThreadPool.runJob(QueuedThreadPool.java:883) at org.eclipse.jetty.util.thread.QueuedThreadPool$Runner.run(QueuedThreadPool.java:1034) at java.lang.Thread.run(Thread.java:748)

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