Individual Study / TMC

The Malaysian Cohort

The Malaysian Cohort

TMC logo
Initiatives -
Objectives: * To study and determine the roles and interaction of genes, environment and lifestyle in various diseases through a large-scale population cohort study; * To discover biomarkers for cancers and other diseases using the genomics and proteomics approach which would eventually lead to early detection and prevention of diseases; * To consolidate and sustain the initiative for research in life sciences through a systematic discovery programme and also international collaborative research; and * To establish a rich database of information and a bank of biospecimens which will become a national resource for research. **managementcohort@gmail.com**
Start Year
2006
Funding
National Biotechnology Division, Ministry of Science, University Kebangsaan Malaysia. Technology and Innovation (MOSTI), Malaysia (ER-05-01-02-MEB001) ,
Supplementary Information
International HundredK+ Cohorts Consortium (IHCC) (66
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Members

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Investigators Contacts
  • Dr Rahmal Jamal
    Universiti Kebangsaan Malaysia

Design

Study design
Population cohort
Follow Up
The follow-up phase commenced in June 2013. Each participant was given a health diary to fill up and return to the TMC office every 6 months. This was to record all illnesses, visits to health facilities, medications and procedures, cost of each treatment and source of payment. Due to the low percentage of the return of these self-report forms, we decided to set up a team to call each participant every 6 months and interviewed them based on the health diary. A comprehensive follow-up is targeted every 5 years, where each participant will again be interviewed, biophysical measurements repeated and biospecimens collected. The National Registration Department (NRD) provided the mortality data and the cause of death every 6 months.
Supplementary Information
http://www.ukm.my/mycohort/ms/penyelidikan-kami/

Marker Paper

Jamal R, Syed Zakaria SZ, Kamaruddin MA, et al. Cohort Profile: The Malaysian Cohort (TMC) project: a prospective study of non-communicable diseases in a multi-ethnic population. Int J Epidemiol. 2015;44(2):423-431. doi:10.1093/ije/dyu089

PUBMED 24729425

Recruitment

Sources of Recruitment
  • Individuals

Number of participants

Number of participants
130,000
Number of participants with biosamples
Supplementary Information
Participants from rural and urban areas as well as from various socioeconomic groups(more than 180 locations entire Malaysia).

Access

Availability of data and biosamples

Data
Biosamples
Other

Availability of access information

On the study website : http://www.ukm.my/mycohort/ms/

By contacting the study representative