Individual Study / STAR 3

Effects of Sensor-Augmented Pump Therapy on Glycemic Variability in Well-Controlled Type 1 Diabetes in the STAR 3 Study

Effects of Sensor-Augmented Pump Therapy on Glycemic Variability in Well-Controlled Type 1 Diabetes in the STAR 3 Study

Initiatives -
Compared with multiple daily injections (MDI), sensor-augmented pump (SAP) insulin therapy may reduce glycemic variability and oxidative stress in type 1 diabetes in a glycosylated hemoglobin (A1C)-independent manner. The STAR 3 study compared SAP with MDI therapy for 1 year. Note: All published information has been collected from the article referenced in the Marker Paper box below. Therefore, there may be variations with more advanced versions of the study.
Start Year
2012
End Year
2012
Funding
J.B.B, Y.C.K., T.B., and S.N.D have received research sup-port from Medtronic, Inc. J.S. and J.B.W. are employees ofMedtronic, Inc

Design

Study design
Clinical trial cohort

Marker Paper

Buse JB, Kudva YC, Battelino T, Davis SN, Shin J, Welsh JB. Effects of sensor-augmented pump therapy on glycemic variability in well-controlled type 1 diabetes in the STAR 3 study. Diabetes Technol Ther. 2012;14(7):644-647. doi:10.1089/dia.2011.0294

PUBMED 22524549

Recruitment

Sources of Recruitment
  • Individuals

Number of participants

Number of participants
496
Number of participants with biosamples

Access

Availability of data and biosamples

Data
Biosamples
Other

Timeline

Population

Subjects with a 1 year prior Type 1 diabetes diagnosis
Selection Criteria
Newborns
Twins
Ethnic Origin
Health Status
  • Type 1 diabetes

Recruitment

Sources of recruitment
  • Specific population

Number of participants

Number of participants
496
Number of participants with biosamples
Data Collection Event
Compared with multiple daily injections (MDI), sensor-augmented pump (SAP) insulin therapy may reduce glycemic variability and oxidative stress in type 1 diabetes in a glycosylated hemoglobin (A1C)-independent manner.
Start Date
2012
End Date
2012
Data sources
  • Smart sensors
    • Sensor- augumented pump