Individual Study / Matcham et al.; BMC Psychiatry. 2019

Remote Assessment of Disease and Relapse in Major Depressive Disorder (RADAR-MDD): A Multi-Centre Prospective Cohort Study Protocol

Remote Assessment of Disease and Relapse in Major Depressive Disorder (RADAR-MDD): A Multi-Centre Prospective Cohort Study Protocol

Initiatives -
This study aims to: 1) determine the usability, feasibility and acceptability of RMT; 2) improve and refine clinical outcome measurement using RMT to identify current clinical state; 3) determine whether RMT can provide information predictive of depressive relapse and other critical outcomes. Note: All published information has been collected from the article referenced in the Marker Paper box below. Therefore, there may be variations with more advanced versions of the study.
Start Year
2019
End Year
2019
Funding
The RADAR-CNS project has received funding from the Innovative MedicinesInitiative 2 Joint Undertaking under grant agreement No 115902. This JointUndertaking receives support from the European Union’s Horizon 2020 re-search and innovation programme and EFPIA (www.imi.europa.eu).

Design

Study design
Patients' cohort

Marker Paper

Matcham F, Barattieri di San Pietro C, Bulgari V, et al. Remote assessment of disease and relapse in major depressive disorder (RADAR-MDD): a multi-centre prospective cohort study protocol. BMC Psychiatry. 2019;19(1):72. Published 2019 Feb 18. doi:10.1186/s12888-019-2049-z

PUBMED 30777041

Recruitment

Sources of Recruitment
  • Individuals

Number of participants

Number of participants
600
Number of participants with biosamples
Supplementary Information
600 participants with a history of depressive disorder

Access

Availability of data and biosamples

Data
Biosamples
Other

Timeline

Population

The 600 participants with a history of depressive disorder.
Selection Criteria
Newborns
Twins
Countries
  • United Kingdom
  • Netherlands
  • Spain
Territory
London, Amsterdam and Barcelona
Ethnic Origin
Health Status
  • The 600 participants with a history of depressive disorder.

Recruitment

Sources of recruitment
  • Specific population

Number of participants

Number of participants
600
Number of participants with biosamples
Data Collection Event
Participants will be asked to wear a wrist-worn activity tracker and download several apps onto their smartphones. These apps will be used to either collect data passively from existing smartphone sensors, or to deliver questionnaires, cognitive tasks, and speech assessments. The wearable device, smartphone sensors and questionnaires will collect data for up to 2-years about participants' sleep, physical activity, stress, mood, sociability, speech patterns, and cognitive function.
Start Date
2019
End Date
2019
Data sources
  • Mobile data collection
    • Smartphone apps
    • Smartwatch and wearables
    • Tablet/laptop