Individual Study / RAAK

Research Arthritis and Articular Cartilage

Research Arthritis and Articular Cartilage

Initiatives -
The RAAK study is aimed at the biobanking of joint materials as well as mesenchymal stem cells and primary chondrocytes from patients and controls in the Leiden University Medical Center and collaborating outpatient clinics in the Leiden area. *Note: All published information has been collected from the article referenced in the Marker Paper box below. Therefore, there may be variations with more advanced versions of the study.*
Dutch Scientific Research council NWO /ZonMW VICI scheme (nr 91816631/528), Dutch Arthritis Society (DAA_10_1-402), and European Commission Seventh Framework programme (TreatOA, 200800).
Supplementary Information
Publication year: 2014


Investigators Contacts
  • Dr. Prof. Yolande F.M. Ramos
    Leiden University Medical Center
  • Dr. Demien Broekhuis
    Leiden University Medical Centre


Study design
Patients' cohort

Marker Paper

Ramos YF, den Hollander W, Bovée JV, Bomer N, van der Breggen R, Lakenberg N, Keurentjes JC, Goeman JJ, Slagboom PE, Nelissen RG, Bos SD, Meulenbelt I. Genes involved in the osteoarthritis process identified through genome wide expression analysis in articular cartilage; the RAAK study. PLoS One. 2014 Jul 23;9(7):e103056. doi: 10.1371/journal.pone.0103056.

PUBMED 25054223


Sources of Recruitment
  • Individuals

Number of participants

Number of participants
Number of participants with biosamples
Supplementary Information
Patients that underwent a joint replacement surgery due to OA


Availability of data and biosamples