Pre- and postnatal exposure periods for child health: Common risks and shared mechanisms
Initiatives
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We especially target the prenatal period to examine if and how prenatal exposures may “program” adaptive biological responses in the fetus and child, with carry-forward effects on brain and somatic health; furthermore, we focus particularly on inflammation as a mediator of environmental exposures because it is a compelling biological mechanism by which a wide range of exposures may shape child neurodevelopment and obesity.
- Start Year
- 2016
- End Year
- 2023
- Funding
- National Institutes of Health
Visit Pre- and postnatal exposure periods for child health: Common risks and shared mechanisms
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Design
- Study design
- Population cohort
- Follow Up
- The 500 children will be extensively studied at newborn, 6 months, 1 year, 2 years, 3 years, and 4 years of age.
Marker Paper
Rasmussen JM, Graham AM, Entringer S, Gilmore JH, Styner M, Fair DA, Wadhwa PD, Buss C. Maternal Interleukin-6 concentration during pregnancy is associated with variation in frontolimbic white matter and cognitive development in early life. Neuroimage. 2019 Jan 15;185:825-835. doi: 10.1016/j.neuroimage.2018.04.020. Epub 2018 Apr 11.
PUBMED 29654875
Recruitment
- Sources of Recruitment
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- Families
Number of participants
- Number of participants
- 500
- Number of participants with biosamples
Access
Availability of data and biosamples
| Data | |
| Biosamples | |
| Other |