Individual Study / PPS

The Primary Prevention Study

The Primary Prevention Study

Initiatives -
1. to analyse the extent to which it was possible to induce changes in risk factors in a randomly selected population sample of middle-aged Swedish men by means of a population-based intervention programme which could be managed by a limited number of physicians and paramedical personnel. 2. to measure the effect of this intervention programme on the incidence of non-fatal and fatal myocardial infarction, stroke and the total death rate in the intervention group compared with two control groups also randomly selected from the general population.
Start Year
End Year
Visit PPS


Investigators Contacts
  • Dr. Prof. Annika Rosengren
    University of Gothenburg


Study design
Follow Up
The first examined group was men born in 1915 and the first screening was completed 1973 with those born in 1925. A second examination started in 1974 and was completed in early spring 1977, and the final examination was performed ten years after the first one, that is between 1980 and 1983.

Marker Paper

Jood K, Jern C, Wilhelmsen L, Rosengren A. Body mass index in mid-life is associated with a first stroke in men: a prospective population study over 28 years. Stroke. 2004 Dec;35(12):2764-9. doi: 10.1161/ Epub 2004 Oct 28.

PUBMED 15514172


Sources of Recruitment
  • Individuals

Number of participants

Number of participants
Number of participants with biosamples
Supplementary Information
All men in Gothenburg born in 1915-1922 and 1924-1925


Availability of data and biosamples