Synchros | OCTO-Twin

Study of Origins of Variance in the Old-Old

Initiatives -

Start Year: 1991
End Year: 2002
Funding: NIH(NIA)
Supplementary Information: https://www.maelstrom-research.org/mica/individual-study/octo-twin

Visit OCTO-Twin

Members

Investigators	Contacts
Dr. Prof. Boo Johansson University of Gothenburg Boo Johansson Title Dr. Prof. Name Boo Johansson Email Boo.Johansson@psy.gu.se Institution University of Gothenburg

Design

Study design: Population cohort
Follow Up: 5 waves of data collection at 2 year intervals(8years follow up).

Marker Paper

Cadar, D, Stephan, BCM, Jagger, C, Johansson, B, Hofer, SM, Piccinin, AM & Muniz-Terrera, G 2015, 'The role of cognitive reserve on terminal decline: A cross-cohort analysis from two European studies: OCTOTwin, Sweden, and Newcastle 85+, UK', International Journal of Geriatric Psychiatry, vol. 31, no. 6, pp. 601- 610. https://doi.org/10.1002/gps.4366

PUBMED 26471722

Recruitment

Sources of Recruitment

Families

Number of participants

Number of participants: 702
Number of participants with biosamples: 552

Access

General Information

Availability of data and biosamples

Data
Biosamples
Other

Availability of access information

By contacting the study representative

Name: FreeMarker template error (DEBUG mode; use RETHROW in production!): The following has evaluated to null or missing: ==> study.model.access_info_representative [in template "libs/study.ftl" at line 597, column 37] ---- Tip: It's the step after the last dot that caused this error, not those before it. ---- Tip: If the failing expression is known to legally refer to something that's sometimes null or missing, either specify a default value like myOptionalVar!myDefault, or use <#if myOptionalVar??>when-present<#else>when-missing. (These only cover the last step of the expression; to cover the whole expression, use parenthesis: (myOptionalVar.foo)!myDefault, (myOptionalVar.foo)?? ---- ---- FTL stack trace ("~" means nesting-related): - Failed at: ${study.model.access_info_representat... [in template "libs/study.ftl" in macro "studyAccessInfo" at line 597, column 35] - Reached through: @studyAccessInfo study=study [in template "libs/study.ftl" in macro "studyAccess" at line 334, column 17] - Reached through: @studyAccess study=study [in template "libs/study.ftl" in macro "studyModel" at line 28, column 11] - Reached through: @studyModel study=study type=type [in template "study.ftl" at line 189, column 9] ---- Java stack trace (for programmers): ---- freemarker.core.InvalidReferenceException: [... Exception message was already printed; see it above ...] at freemarker.core.InvalidReferenceException.getInstance(InvalidReferenceException.java:134) at freemarker.core.UnexpectedTypeException.newDescriptionBuilder(UnexpectedTypeException.java:85) at freemarker.core.UnexpectedTypeException.(UnexpectedTypeException.java:48) at freemarker.core.NonHashException.(NonHashException.java:49) at freemarker.core.Dot._eval(Dot.java:48) at freemarker.core.Expression.eval(Expression.java:101) at freemarker.core.DefaultToExpression._eval(DefaultToExpression.java:88) at freemarker.core.Expression.eval(Expression.java:101) at freemarker.core.DollarVariable.calculateInterpolatedStringOrMarkup(DollarVariable.java:100) at freemarker.core.DollarVariable.accept(DollarVariable.java:63) at freemarker.core.Environment.visit(Environment.java:331) at freemarker.core.Environment.visit(Environment.java:337) at freemarker.core.Environment.visit(Environment.java:373) at freemarker.core.Environment.invokeMacroOrFunctionCommonPart(Environment.java:872) at freemarker.core.Environment.invokeMacro(Environment.java:809) at freemarker.core.UnifiedCall.accept(UnifiedCall.java:83) at freemarker.core.Environment.visit(Environment.java:331) at freemarker.core.Environment.visit(Environment.java:373) at freemarker.core.Environment.invokeMacroOrFunctionCommonPart(Environment.java:872) at freemarker.core.Environment.invokeMacro(Environment.java:809) at freemarker.core.UnifiedCall.accept(UnifiedCall.java:83) at freemarker.core.Environment.visit(Environment.java:331) at freemarker.core.Environment.visit(Environment.java:337) at freemarker.core.Environment.visit(Environment.java:373) at freemarker.core.Environment.invokeMacroOrFunctionCommonPart(Environment.java:872) at freemarker.core.Environment.invokeMacro(Environment.java:809) at freemarker.core.UnifiedCall.accept(UnifiedCall.java:83) at freemarker.core.Environment.visit(Environment.java:331) at freemarker.core.Environment.visit(Environment.java:337) at freemarker.core.Environment.process(Environment.java:310) at freemarker.template.Template.process(Template.java:383) at org.springframework.web.servlet.view.freemarker.FreeMarkerView.processTemplate(FreeMarkerView.java:368) at org.springframework.web.servlet.view.freemarker.FreeMarkerView.doRender(FreeMarkerView.java:285) at org.springframework.web.servlet.view.freemarker.FreeMarkerView.renderMergedTemplateModel(FreeMarkerView.java:235) at org.springframework.web.servlet.view.AbstractTemplateView.renderMergedOutputModel(AbstractTemplateView.java:167) at org.springframework.web.servlet.view.AbstractView.render(AbstractView.java:304) at org.springframework.web.servlet.DispatcherServlet.render(DispatcherServlet.java:1286) at org.springframework.web.servlet.DispatcherServlet.processDispatchResult(DispatcherServlet.java:1041) at org.springframework.web.servlet.DispatcherServlet.doDispatch(DispatcherServlet.java:984) at org.springframework.web.servlet.DispatcherServlet.doService(DispatcherServlet.java:901) at org.springframework.web.servlet.FrameworkServlet.processRequest(FrameworkServlet.java:970) at org.springframework.web.servlet.FrameworkServlet.doGet(FrameworkServlet.java:861) at javax.servlet.http.HttpServlet.service(HttpServlet.java:687) at org.springframework.web.servlet.FrameworkServlet.service(FrameworkServlet.java:846) at javax.servlet.http.HttpServlet.service(HttpServlet.java:790) at org.eclipse.jetty.servlet.ServletHolder.handle(ServletHolder.java:799) at org.eclipse.jetty.servlet.ServletHandler$ChainEnd.doFilter(ServletHandler.java:1631) at org.obiba.mica.web.filter.ClickjackingHttpHeadersFilter.doFilter(ClickjackingHttpHeadersFilter.java:41) at org.eclipse.jetty.servlet.FilterHolder.doFilter(FilterHolder.java:193) at org.eclipse.jetty.servlet.ServletHandler$Chain.doFilter(ServletHandler.java:1601) at com.codahale.metrics.servlet.AbstractInstrumentedFilter.doFilter(AbstractInstrumentedFilter.java:97) at org.eclipse.jetty.servlet.FilterHolder.doFilter(FilterHolder.java:193) at org.eclipse.jetty.servlet.ServletHandler$Chain.doFilter(ServletHandler.java:1601) at org.obiba.mica.config.WebConfiguration$NoTraceFilter.doFilter(WebConfiguration.java:298) at org.eclipse.jetty.servlet.FilterHolder.doFilter(FilterHolder.java:193) at org.eclipse.jetty.servlet.ServletHandler$Chain.doFilter(ServletHandler.java:1601) at org.eclipse.jetty.websocket.server.WebSocketUpgradeFilter.doFilter(WebSocketUpgradeFilter.java:228) at org.eclipse.jetty.servlet.FilterHolder.doFilter(FilterHolder.java:193) at org.eclipse.jetty.servlet.ServletHandler$Chain.doFilter(ServletHandler.java:1601) at org.obiba.shiro.web.filter.AuthenticationFilter.doFilterInternal(AuthenticationFilter.java:158) at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107) at org.eclipse.jetty.servlet.FilterHolder.doFilter(FilterHolder.java:193) at org.eclipse.jetty.servlet.ServletHandler$Chain.doFilter(ServletHandler.java:1601) at org.springframework.web.filter.RequestContextFilter.doFilterInternal(RequestContextFilter.java:99) at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107) at org.eclipse.jetty.servlet.FilterHolder.doFilter(FilterHolder.java:193) at org.eclipse.jetty.servlet.ServletHandler$Chain.doFilter(ServletHandler.java:1601) at org.springframework.web.filter.HttpPutFormContentFilter.doFilterInternal(HttpPutFormContentFilter.java:109) at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107) at org.eclipse.jetty.servlet.FilterHolder.doFilter(FilterHolder.java:193) at org.eclipse.jetty.servlet.ServletHandler$Chain.doFilter(ServletHandler.java:1601) at org.springframework.web.filter.HiddenHttpMethodFilter.doFilterInternal(HiddenHttpMethodFilter.java:93) at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107) at org.eclipse.jetty.servlet.FilterHolder.doFilter(FilterHolder.java:193) at org.eclipse.jetty.servlet.ServletHandler$Chain.doFilter(ServletHandler.java:1601) at org.springframework.web.filter.CharacterEncodingFilter.doFilterInternal(CharacterEncodingFilter.java:197) at org.springframework.web.filter.OncePerRequestFilter.doFilter(OncePerRequestFilter.java:107) at org.eclipse.jetty.servlet.FilterHolder.doFilter(FilterHolder.java:193) at org.eclipse.jetty.servlet.ServletHandler$Chain.doFilter(ServletHandler.java:1601) at org.eclipse.jetty.servlet.ServletHandler.doHandle(ServletHandler.java:548) at org.eclipse.jetty.server.handler.ScopedHandler.handle(ScopedHandler.java:143) at org.eclipse.jetty.security.SecurityHandler.handle(SecurityHandler.java:600) at org.eclipse.jetty.server.handler.HandlerWrapper.handle(HandlerWrapper.java:127) at org.eclipse.jetty.server.handler.ScopedHandler.nextHandle(ScopedHandler.java:235) at org.eclipse.jetty.server.session.SessionHandler.doHandle(SessionHandler.java:1624) at org.eclipse.jetty.server.handler.ScopedHandler.nextHandle(ScopedHandler.java:233) at org.eclipse.jetty.server.handler.ContextHandler.doHandle(ContextHandler.java:1434) at org.eclipse.jetty.server.handler.ScopedHandler.nextScope(ScopedHandler.java:188) at org.eclipse.jetty.servlet.ServletHandler.doScope(ServletHandler.java:501) at org.eclipse.jetty.server.session.SessionHandler.doScope(SessionHandler.java:1594) at org.eclipse.jetty.server.handler.ScopedHandler.nextScope(ScopedHandler.java:186) at org.eclipse.jetty.server.handler.ContextHandler.doScope(ContextHandler.java:1349) at org.eclipse.jetty.server.handler.ScopedHandler.handle(ScopedHandler.java:141) at org.eclipse.jetty.server.handler.gzip.GzipHandler.handle(GzipHandler.java:763) at org.eclipse.jetty.server.handler.HandlerWrapper.handle(HandlerWrapper.java:127) at org.eclipse.jetty.server.Server.handle(Server.java:516) at org.eclipse.jetty.server.HttpChannel.lambda$handle$1(HttpChannel.java:400) at org.eclipse.jetty.server.HttpChannel.dispatch(HttpChannel.java:645) at org.eclipse.jetty.server.HttpChannel.handle(HttpChannel.java:392) at org.eclipse.jetty.server.HttpConnection.onFillable(HttpConnection.java:277) at org.eclipse.jetty.io.AbstractConnection$ReadCallback.succeeded(AbstractConnection.java:311) at org.eclipse.jetty.io.FillInterest.fillable(FillInterest.java:105) at org.eclipse.jetty.io.ChannelEndPoint$1.run(ChannelEndPoint.java:104) at org.eclipse.jetty.util.thread.strategy.EatWhatYouKill.runTask(EatWhatYouKill.java:338) at org.eclipse.jetty.util.thread.strategy.EatWhatYouKill.doProduce(EatWhatYouKill.java:315) at org.eclipse.jetty.util.thread.strategy.EatWhatYouKill.tryProduce(EatWhatYouKill.java:173) at org.eclipse.jetty.util.thread.strategy.EatWhatYouKill.run(EatWhatYouKill.java:131) at org.eclipse.jetty.util.thread.ReservedThreadExecutor$ReservedThread.run(ReservedThreadExecutor.java:409) at org.eclipse.jetty.util.thread.QueuedThreadPool.runJob(QueuedThreadPool.java:883) at org.eclipse.jetty.util.thread.QueuedThreadPool$Runner.run(QueuedThreadPool.java:1034) at java.lang.Thread.run(Thread.java:748)

Individual Study / OCTO-Twin