Individual Study / OBS

Ontario Birth Study

Ontario Birth Study

OBS logo
Initiatives -
To develop a platform for research on pregnancy complications, maternal and infant health, and to assemble a cohort for future studies on the developmental origins of health and disease. The main goals are: Examples of these goals are: 1. to identify informative biomarkers and define molecular mechanisms responsible for the major pregnancy complications such as growth restriction, preeclampsia and preterm birth 2. to determine how adversity during pregnancy and early life impact the establishment of developmental trajectories to later life health, learning and social functioning, and 3. through the promotion of interventions that seek to optimize individual developmental trajectories, to enhance developmental potential and prevent or mitigate the impact of early adversity. **** ; ****
Start Year
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Investigators Contacts
  • Dr. Prof. Howard Berger
    St. Michael’s Hospital


Study design
Population cohort
Follow Up
The study continue to follow up children from the OBS mothers at ages 8 months, 24 months, 36 months and 4.5 years.

Marker Paper

Anderson LN, Knight JA, Hung RJ, et al. The Ontario Birth Study: A prospective pregnancy cohort study integrating perinatal research into clinical care. Paediatr Perinat Epidemiol. 2018;32:290–301.

PUBMED 29750375


Sources of Recruitment
  • Individuals
  • Families

Number of participants

Number of participants
Number of participants with biosamples
Supplementary Information
INCLUSION CRITERIA: Pregnant women less than 17 weeks gestational age - at least 18 years of age - English speaking,delivering at an OBS Hospital - antenatal care at an OBS Hospital.


Availability of data and biosamples


Availability of access information

On the study website :