New Hampshire Birth Cohort Study (NHBCS)
1. Leveraging the extant NHBCS to perform targeted and unsupervised metabolomic analyses of 1,000 cord blood samples and 250 paired maternal gestational blood samples, and assess associations with exposures, early growth, and the infant microbiome; 2. expanding data acquisition, sample collection and participant accrual to more precisely characterize exposures and timing of early life exposures by obtaining urinary metallome and metal metabolomic measurements, and exposome monitoring data from the first trimester of pregnancy, along with spatial analysis of naturally shed teeth for prenatal metal concentrations; 3. extending follow-up to identify childhood exposures to contaminants (through biomarkers and personal monitors); the home environment (e.g., physical activity and sleep patterns, food environment, green, blue and white space, and media usage); and medical exposures (e.g., prescription and non-prescription medications and surgical interventions) that relate to fetal and childhood growth, obesity at age 3 years, respiratory infection and asthma by age 5 years, and pulmonary function data at age 7.5 years.
- Start Year
- National Institutes of Health (NIH)
- Study design
- Population cohort
- Sources of Recruitment
Number of participants
- Number of participants
- Number of participants with biosamples
- Supplementary Information
- The study has recruited over 2,500 mother-infant pairs (over 4,000 individuals)
Availability of data and biosamples
No coverage data about the variables classifications are available.