Individual Study / N2

The Neighborhoods and Networks (N2) Cohort Study

The Neighborhoods and Networks (N2) Cohort Study

Initiatives -
The overall objective of this study is to utilize real-time geospatial methods alongside in-depth assessments of multiple network typologies to investigate cross-sectional and longitudinal associations of neighborhood-level (e.g., poverty, HIV prevalence, and access to healthcare) and network-level (e.g., network size, frequency of communication with network members, and material support) factors on HIV prevention and care outcomes among Black MSM in areas that are home to large groups of this population in the U.S., namely the metropolitan statistical areas (MSAs) of Chicago, Illinois, Jackson, Mississippi, and New Orleans, Louisiana. In particular, the aim of this study is to examine the independent role of neighborhoods and networks in HIV outcomes, as well as the synergistic role of neighborhoods and networks in HIV outcomes. Note: All published information has been collected from the article referenced in the Marker Paper box below. Therefore, there may be variations with more advanced versions of the study.
Start Year
2018
Funding
The Neighborhoods and Networks (N2) Cohort Study was funded through a grant from the National Institute on Mental Health (Grant Number: R01MH112406; Principal Investigators: Dustin T. Duncan, ScD and John A. Schneider, MD, MPH) and a cooperative agreement with the Centers for Disease Control and Prevention under the Minority HIV/AIDS Research Initiative (Grant Number: U01PS005122; Principal Investigator: Dustin T. Duncan, ScD). The original study samples at each site were funded through grants from the National Institute on Drug Abuse and the National Institute on Allergy and Infectious Diseases (Grant Numbers: R01DA033875 and R01AI120700; Principal Investigator: John A. Schneider, MD, MPH), a grant from the National Institute on Drug Abuse (Grant Number: R03DA039748; Principal Investigator: Dustin T. Duncan, ScD) and through a cooperative agreement with the Centers for Disease Control and Prevention under the Minority HIV/AIDS Research Initiative (Grant Number: U01PS003315; Principal Investigator: DeMarc A. Hickson, PhD) respectively. William Goedel is supported by Brown University Clinical and Community-Based HIV/AIDS Training Fellowship, funded by the National Institute of Mental Health (Grant Number: R25MH083620). Basile Chaix was supported by Inserm and by the European Research Council. Steven Safren is supported by a grant from the National Institute on Drug Abuse (Grant Number: K24DA040489).

Design

Study design
Population cohort
Follow Up
The sample includes Black MSM participants in Chicago recruited via respondent-driven sampling and assessed every six months over two years of follow-up. Participants enrolled in Jackson and New Orleans are being recruited through existing health and community services and assessed every six months over one year of follow-up

Marker Paper

The Social Context of HIV Prevention and Care among Black Men Who Have Sex with Men in Three U.S. Cities: The Neighborhoods and Networks (N2) Cohort Study. Int J Environ Res Public Health. 2019;16(11):1922. Published 2019 May 30. doi:10.3390/ijerph16111922

PUBMED 31151275

Number of participants

Number of participants
600
Number of participants with biosamples

Access

Availability of data and biosamples

Data
Biosamples
Other

Timeline

Population

The study design includes the use of real-time geospatial methods and in-depth assessments of multiple network typologies to investigate the impact of neighborhood and network-level factors on HIV prevention and treatment among Black MSM residing in longstanding priority HIV elimination areas in the U.S., namely Chicago, Illinois and in the Deep South (Jackson, Mississippi and New Orleans, Louisiana) (n = 450, n = 50, and n = 100, respectively).
Selection Criteria
Newborns
Twins
Countries
  • United States of America
Territory
Chicago, Illinois and in the Deep South (Jackson, Mississippi and New Orleans, Louisiana)
Ethnic Origin
Health Status

Recruitment

Sources of recruitment
  • Specific population

Number of participants

Number of participants
600
Number of participants with biosamples
Data Collection Event
Mobility within and between neighborhoods is being assessed using global positioning system (GPS) technology. Social and sexual networks among BlackMSMare being studied through egocentric network inventories as well as newer methods of creating meso-level networks that involve social media (Facebook) and mobile phone contacts.
Start Date
2018
End Date
2018
Data sources
  • Mobile data collection
    • Mobile phone
  • Social media
    • Facebook
  • Geospatial technology
    • Global navigation satellite systems (GNSS) (e.g. GPS, GLONASS, Galileo, etc.)