Mild Stroke Study II
Initiatives
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To determine the tracer kinetic modelling approach most suitable for assessing subtle BBB leakage using a data-driven approach, to determine its validity both in theory and experimentally and to obtain tracer kinetic parameters for normal-appearing tissues and lesions.
*Note: All published information has been collected from the article referenced in the Marker Paper box below. Therefore, there may be variations with more advanced versions of the study.*
- Start Year
- 2010
- End Year
- 2015
- Funding
- This work was funded by Wellcome Trust (SDM, recruitment and MRI scanning costs; grant 088134/Z/09/A), Row Fogo Charitable Trust (MCVH, AKH), Age UK (SMM), NHS Lothian Research and Development Office (MJT), Scottish Funding Council and the Chief Scientist Office of Scotland for funding the Scottish Imaging Network: A Platform for Scientific Excellence (“SINAPSE”; JMW, radiography staff).
| Investigators | Contacts |
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Design
- Study design
- Patients' cohort
- Follow Up
- Baseline ( < 2 weeks of stroke)- follow ups at 1-3 months and 1 year.
Marker Paper
Heye, A. K., Thrippleton, M. J., Armitage, P. A., Valdés Hernández, M., Makin, S. D., Glatz, A., Sakka, E., & Wardlaw, J. M. (2016). Tracer kinetic modelling for DCE-MRI quantification of subtle blood-brain barrier permeability. NeuroImage, 125, 446–455. https://doi.org/10.1016/j.neuroimage.2015.10.018
Recruitment
- Sources of Recruitment
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- Individuals
Number of participants
- Number of participants
- 264
- Number of participants with biosamples
- Supplementary Information
- Aged 30-90 years of age
Access
Availability of data and biosamples
| Data | |
| Biosamples | |
| Other |