Individual Study / CFAS

Study design

Population cohort

Follow Up

The follow-up consisted of an assessment (designed to be conducted 1 month after the screening interview) and annual interview (designed to be conducted 1 year after the screening interview). At the assessment and biannual follow-up interview permission was sought to approach and interview a relative or carer to ask for an objective account of the respondent’s health and abilities. Six years after the initial screening interview, all respondents in the assessed groups were interviewed. At 8 years only those who had indicated an intention to donate brain tissue were re-interviewed. At 10 years all survivors from the responding group of the complete study were re-contacted for interview.

Minett, T., Classey, J., Matthews, F. E., Fahrenhold, M., Taga, M., Brayne, C., Ince, P. G., Nicoll, J. A., Boche, D., & MRC CFAS (2016). Microglial immunophenotype in dementia with Alzheimer's pathology. Journal of neuroinflammation, 13(1), 135. https://doi.org/10.1186/s12974-016-0601-z

PUBMED 16980700

Sources of Recruitment

• Individuals

Number of participants

13,004

Number of participants with biosamples