Individual Study / MPLS

Minneapolis Childhood Cohort Studies

Minneapolis Childhood Cohort Studies

Initiatives -
* 1978 cohort: To examine environmental and familial correlates of childhood blood pressure (BP). * 1996 cohort (subsample of 1978 cohort): To assess the effect of body size and change in body size during childhood and adolescence on the cardiovascular risk factors of fasting insulin, lipids, and systolic blood pressure (SBP) in young adulthood. *Note: All published information has been collected from the article referenced in the Marker Paper box below. Therefore, there may be variations with more advanced versions of the study.*
Start Year
1978
End Year
1996
Funding
NIH Grants (HL 52851, M01-RR-00400 and DK72124).

Members

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Investigators Contacts
  • MD Julia Steinberger
    University of Minnesota Medical Center
  • Dr Alan Sinaiko
    University of Minnesota Medical School (A.R.S.)

Design

Study design
Population cohort
Follow Up
In the 1978 cohort children were examined approximately twice yearly through their grade school and junior high school years and once yearly during high school. At each examination, measurements of height, weight, and blood pressure were obtained. A post– high school (PH) examination was conducted within 2 years of graduation from high school, at which time blood pressure and anthropometric data were obtained. This group of 817 was recontacted 5 years after the PH visit, and 679 were reexamined in 1993 to 1995 (age, 23.6 years), forming the 1996 sample study. In addition to the anthropometric and blood pressure data, a fasting blood sample was obtained at the 1993 to 1995 visit for insulin, cholesterol, HDL cholesterol (HDL-C),triglycerides, and LDL cholesterol (LDL-C).

Marker Paper

Sinaiko AR, Donahue RP, Jacobs DR Jr, Prineas RJ. Relation of weight and rate of increase in weight during childhood and adolescence to body size, blood pressure, fasting insulin, and lipids in young adults. The Minneapolis Children's Blood Pressure Study. Circulation. 1999 Mar 23;99(11):1471-6. doi: 10.1161/01.cir.99.11.1471.

PUBMED 10086972

Recruitment

Sources of Recruitment
  • Individuals

Number of participants

Number of participants
1,574
Number of participants with biosamples

Access

Availability of data and biosamples

Data
Biosamples
Other