Individual Study / MORGAM

The MOnica Risk, Genetics, Archiving and Monograph Study

The MOnica Risk, Genetics, Archiving and Monograph Study

MORGAM logo
Initiatives -
To explore the relationships between the development of cardiovascular diseases and their classic and genetic risk factors. MORGAM was designed with the overall aim of eventually studying a limited number of well-defined phenotypes and several hundred genetic factors simultaneously by pooling the risk-factor data collected in the MONICA cross-sectional surveys, adding follow-up and genotyping, and including other relevant cohorts.
Start Year
1982
End Year
2014
Funding
Currently: European Union, THL, other research institutes and universities participating in the study; Formerly also: The Academy of Finland, Medical Research Council of the UK.
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Members

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Investigators Contacts
  • Kari Kuulasmaa
    National Institute for Health and Welfare
  • Prof Aluns Evans
    Queen's University Belfast

Design

Study design
Population cohort
Follow Up
All the cohorts were examined once at baseline. The length of the follow-up period varies between centres. Generally the follow up of the cohorts is for coronary heart disease (CHD) events, stroke, and total mortality and most cohorts are also able to provide a DNA sample.

Marker Paper

Evans A, Salomaa V, Kulathinal S, Asplund K, Cambien F, Ferrario M, Perola M, Peltonen L, Shields D, Tunstall-Pedoe H, Kuulasmaa K; MORGAM Project. MORGAM (an international pooling of cardiovascular cohorts). Int J Epidemiol. 2005 Feb;34(1):21-7. doi: 10.1093/ije/dyh327. Epub 2004 Nov 23.

PUBMED 15561751

Recruitment

Sources of Recruitment
  • Individuals

Number of participants

Number of participants
204,192
Number of participants with biosamples

Access

Availability of data and biosamples

Data
Biosamples
Other

Availability of access information

On the study website : https://www.thl.fi/morgam/