Individual Study / MAVAN

Maternal Adversity, Vulnerability and Neurodevelopment

Maternal Adversity, Vulnerability and Neurodevelopment

Initiatives -
Maternal Adversity Vulnerability and Neurodevelopment (MAVAN) project is a prospective community-based, pregnancy and birth cohort of Canadian mother-child dyads. The main objective of MAVAN project is to examine the pre- and postnatal influences, and their interaction, in determining individual differences in children development. The MAVAN project is designed to examine the consequences of fetal adversity as a function of the quality of the postnatal environment, focusing on mother-infant interactions.
Start Year
2003
End Year
2017
Funding
Douglas Mental Health University Institute
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Members

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Investigators Contacts
  • Dr. Prof. Michael Meaney
    McGill University
  • Dr. Helene Gaudreau
    McGill University

Design

Study design
Population cohort
Follow Up
The mothers were recruited between 13 to 20 weeks and interviewed between 24 to 36 weeks of pregnancy while dyads were followed from three-month post-partum onward. Dyads were assessed at 3, 6, 12, 18 months, and yearly from age 24 months onwards. Mothers were first assessed during their pregnancy (∼26 weeks) and then followed at multiple time points that included home visits and laboratory sessions.

Marker Paper

O'Donnell KA, Gaudreau H, Colalillo S, Steiner M, Atkinson L, Moss E, Goldberg S, Karama S, Matthews SG, Lydon JE et al. 2014. The maternal adversity, vulnerability and neurodevelopment project: theory and methodology. Can J Psychiatry. 59(9):497-508.

PUBMED 25565695

Recruitment

Sources of Recruitment
  • Families

Number of participants

Number of participants
1,249
Number of participants with biosamples
Supplementary Information
Our community sample consisted of mothers recruited in Montréal (Québec) and Hamilton (Ontario), Canada, at 13 to 20 weeks' gestation.

Access

Availability of data and biosamples

Data
Biosamples
Other