35th Multicenter Airway Research Collaboration / 43rd Multicenter Airway Research Collaboration
Initiatives
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Early identification of modifiable risk factors and the heterogeneity of asthma. The objetives are:
1. we will investigate the relation of the airway microbiome in early infancy to risk of age 6y asthma among infants with severe bronchiolitis (MARC-35).
2. we will do the same but among healthy infants (MARC-43).
3. we will investigate the relation of longitudinal patterns of the airway microbiome (e.g., infancy, age 3y, age 6y) to risk of childhood asthma in the two cohorts combined.
- Start Year
- 2014
- Funding
- National Institute of Child Health and Development (NICHD)
Visit MARC-35 / MARC 43
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Design
- Study design
- Patients' cohort
- Follow Up
- Follow-up data include biannual parent interviews and medical records to age 5 years
Marker Paper
Blackwell CK, Hartstein LE, Elliott AJ, Forrest CB, Ganiban J, Hunt KJ, Camargo CA Jr, LeBourgeois MK; program collaborators for Environmental influences on Child Health Outcomes (ECHO). Better sleep, better life? How sleep quality influences children's life satisfaction. Qual Life Res. 2020 Sep;29(9):2465-2474. doi: 10.1007/s11136-020-02491-9. Epub 2020 May 12.
PUBMED 32399666
Recruitment
- Sources of Recruitment
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- Individuals
Number of participants
- Number of participants
- 921
- Number of participants with biosamples
- Supplementary Information
- 17-center prospective cohort study that completed enrollment of 921 hospitalized infants with bronchiolitis in 2014
Access
Availability of data and biosamples
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Biosamples | |
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