Individual Study / MARC-35 / MARC 43

35th Multicenter Airway Research Collaboration / 43rd Multicenter Airway Research Collaboration

35th Multicenter Airway Research Collaboration / 43rd Multicenter Airway Research Collaboration

Initiatives -
Early identification of modifiable risk factors and the heterogeneity of asthma. The objetives are: 1. we will investigate the relation of the airway microbiome in early infancy to risk of age 6y asthma among infants with severe bronchiolitis (MARC-35). 2. we will do the same but among healthy infants (MARC-43). 3. we will investigate the relation of longitudinal patterns of the airway microbiome (e.g., infancy, age 3y, age 6y) to risk of childhood asthma in the two cohorts combined.
Start Year
2014
Funding
National Institute of Child Health and Development (NICHD)
Visit MARC-35 / MARC 43

Members

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Investigators Contacts
  • MD. Prof. Carlos Camargo
    Massachusetts General Hospital

Design

Study design
Patients' cohort
Follow Up
Follow-up data include biannual parent interviews and medical records to age 5 years

Marker Paper

Blackwell CK, Hartstein LE, Elliott AJ, Forrest CB, Ganiban J, Hunt KJ, Camargo CA Jr, LeBourgeois MK; program collaborators for Environmental influences on Child Health Outcomes (ECHO). Better sleep, better life? How sleep quality influences children's life satisfaction. Qual Life Res. 2020 Sep;29(9):2465-2474. doi: 10.1007/s11136-020-02491-9. Epub 2020 May 12.

PUBMED 32399666

Recruitment

Sources of Recruitment
  • Individuals

Number of participants

Number of participants
921
Number of participants with biosamples
Supplementary Information
17-center prospective cohort study that completed enrollment of 921 hospitalized infants with bronchiolitis in 2014

Access

Availability of data and biosamples

Data
Biosamples
Other