Individual Study / Mano a Mano Cohort

Mexican American (Mano a Mano) Cohort

Mexican American (Mano a Mano) Cohort

Initiatives -
The overarching aim of this cohort is to understand cancer and other chronic disease risk and protective factors as they emerge in the Mexican American population undergoing social changes, and to use this information to facilitate the development of population-specific prevention strategies for cancer and cancer-predisposing conditions, such as obesity and diabetes.
Start Year
End Year
The Cohort receives funds collected pursuant to the Comprehensive Tobacco Settlement of 1998 and appropriated by the 76th Legislature to the University of Texas MD Anderson Cancer Center; from the Caroline W Law Fund for Cancer Prevention; and from the Dan Duncan Family Institute for Risk Assessment and Cancer Prevention.
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Investigators Contacts
  • MD Henry F. Gomez
    University of Texas MD Anderson Cancer Center
  • MD. Prof Shine Chang
    University of Texas MD Anderson Cancer Center


Study design
Population cohort
Follow Up
Participants have been actively followed up via annual telephone re-contact to update selected exposures and new diagnosis of selected chronic diseases, including cancer, cardiovascular disease, asthma, chronic obstructive pulmonary disease and diabetes. Ongoing attempts are madeto contact all participants at least once per year.

Marker Paper

Chow WH, Chrisman M, Daniel CR, Ye Y, Gomez H, Dong Q, Anderson CE, Chang S, Strom S, Zhao H, Wu X. Cohort Profile: The Mexican American Mano a Mano Cohort. Int J Epidemiol. 2017 Apr 1;46(2):e3. doi: 10.1093/ije/dyv016.

PUBMED 25747868


Sources of Recruitment
  • Individuals

Number of participants

Number of participants
Number of participants with biosamples


Availability of data and biosamples


Availability of access information

On the study website :

By contacting the study representative