Individual Study / INMA

Infancia y medio ambiente

Infancia y medio ambiente

INMA logo
Initiatives -
* To describe prenatal and postnatal exposure to common contaminants (air and water) and internal dose of xenobiotics, * To measure its association with reproductive disorders and intrauterine and childhood neuro-immuno-endocrine development, * To assess the modifying role of diet, breastfeeding and certain genetic polymorphisms that can protect the child from the effect of the environment.
Start Year
1997
Funding
The INMA project has been supported by the Instituto de Salud Carlos III, Red de Centros de investigación en Epidemiología y Salud Pública (RCESP) and CIBER Epidemiología y Salud Pública (CIBERESP), and in part by the Fondo de Investigación Sanitaria, the European Union’s 6th and 7th Framework Programmes (Hiwate, Escape, Hitea and Contamed projects), the Ministerio de Educación y Ciencia, the Generalitat de Catalunya, the Centre for Research in Environmental Epidemiology (CREAL) of Barcelona, the Fundacio ́La Caixa, the Fundacio ́Roger Torne ́,the Consejería de Salud de Andalucía, the Junta de Andalucía, the Conselleria de Sanitat de la Generalitat Valenciana, the CAJASTUR—Caja Asturias, the Spanish Association against the Cancer (AECC) (Delegación Provincial Asturias), the Departamento de Sanidad-Gobierno Vasco, the Diputación Floral de Gipuzkoa, the University of Oviedo, the KUTXA – Caja Gipuzkoa San Sebastián and the city councils of Zumarraga, Urretxu, Legazpi, Azpeitia, Beasain and Azkoitia in Gipuzkoa.
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Members

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Investigators Contacts
  • Data Manager Lourdes Cirugeda
    Instituto de Salud Global
  • MD, Dr. Mònica Guxens
    Centre for Research in Environmental Epidemiology
  • Director Jordi Sunyer
    Instituto de Salud Global

Design

Study design
Population cohort
Follow Up
In all cohorts there were visits: at pregnancy, childbirth, at age 1 and at age 4. In Ribera d’Ebre and Granada, the visits were made at birth, at age 1 and at age 4. Although the mothers were not followed up during pregnancy, they answered a complete retrospective questionnaire on the pregnancy. In Menorca, the follow up began during pregnancy, and it was continued at childbirth, 3 months, age 1, age 2, age 3, age 4, age 6, age 7.5 and age 10.5. In the 4 new cohorts the first visit was during the first trimester of pregnancy and it was repeated in the second and third trimesters, at childbirth, at 6 months (only in Sabadell and Asturias), at the 12-18 months, and at 2-2,5 and 4-5 years. The visits will continue throughout his life if there is enough funding.
Supplementary Information
http://epinut.edu.umh.es/en/estudio-infancia-y-medio-ambiente-estudio-inma/

Marker Paper

Guxens M, Ballester F, Espada M, Fernández MF, Grimalt JO, Ibarluzea J, Olea N, Rebagliato M, Tardón A, Torrent M, Vioque J, Vrijheid M, Sunyer J; INMA Project. Cohort Profile: the INMA--INfancia y Medio Ambiente--(Environment and Childhood) Project. Int J Epidemiol. 2012 Aug;41(4):930-40. doi: 10.1093/ije/dyr054. Epub 2011 Apr 5..

PUBMED 21471022

Recruitment

Sources of Recruitment
  • Families
  • Other : Pregnant women and their newborns.

Number of participants

Number of participants
3,768
Number of participants with biosamples

Access

Availability of data and biosamples

Data
Biosamples
Other

Availability of access information

On the study website : https://www.proyectoinma.org/