Individual Study / Identifying newborns at risk of adverse neurodevelopmental outcomes and obesity from air pollution

Identifying newborns at risk of adverse neurodevelopmental outcomes and obesity from air pollution

Identifying newborns at risk of adverse neurodevelopmental outcomes and obesity from air pollution

Initiatives -
The goal of the Columbia Center for Children’s Environmental Health (CCCEH) is to contribute to the ECHO consortium and to develop, validate, and implement an urgently needed new biomarker measurable in an easy-to-obtain, small-volume cord blood sample that reflects prenatal exposure to widespread environmental pollutants, polycyclic aromatic hydrocarbons (PAH), and is predictive of risk of adverse outcomes in the domains of obesity and neurodevelopment.
Start Year
2016
End Year
2023
Funding
National Insitutes of Health
Visit Identifying newborns at risk of adverse neurodevelopmental outcomes and obesity from air pollution

Members

Download
Investigators Contacts
  • Dr. Prof. Julie Beth Herbstman
    Columbia University Mailman School of Public Health
  • MD. Prof Susan Laessig
    Georgetown University School of Medicine

Design

Study design
Population cohort

Marker Paper

Wang Y, Qian M, Tang D, Herbstman J, Perera F, Wang S. A powerful and flexible weighted distance-based method incorporating interactions between DNA methylation and environmental factors on health outcomes. Bioinformatics. 2020 Feb 1;36(3):653-659. doi: 10.1093/bioinformatics/btz630.

PUBMED 31504174

Recruitment

Sources of Recruitment
  • Families

Number of participants

Number of participants
1,048
Number of participants with biosamples

Access

Availability of data and biosamples

Data
Biosamples
Other