Individual Study / HOORN

Hoorn Study

Hoorn Study

Initiatives -
Start Year
End Year
Funding for the Hoorn Study was provided by several different sponsors at certain points in time, including: the VU University Medical Center of Amsterdam, the Netherlands Organization for Scientific Research (NWO), the Netherlands Organization for Health Research and Development (ZonMW), the Dutch Diabetes Research Foundation and the Netherlands Heart Foundation.


Investigators Contacts
  • Dr. Femke Rutters
    VU Medical Centre


Study design
Population cohort
Follow Up
Participants from the Hoorn Study have been followed up via several visits to our study centre and via examinin their medical records. A physical re-examination was conducted in 1990-91, which repeated the measurements from the baseline visit with additional extensive diabetes complications measurements. The follow-up visits were repeated in 1996-98, 2000-01, 2005-07 and 2007-09. In addition to physical follow-up visits, all participants were still actively followed up for vital status by linkage with the municipality register and for occurrence of chronic diseases, with a special focus on cardiovascular disease and cancer as well as cause-specific mortality, by checking their medical records until January 2009.

Marker Paper

Rutters F, Nijpels G, Elders P, Stehouwer CDA, van der Heijden AA, Groeneveld L, 't Hart LM, Dekker JM, Beulens JWJ. Cohort Profile: The Hoorn Studies. Int J Epidemiol. 2018 Apr 1;47(2):396-396j. doi: 10.1093/ije/dyx227. Erratum in: Int J Epidemiol. 2020 Feb 1;49(1):357.

PUBMED 29244153


Sources of Recruitment
  • Individuals

Number of participants

Number of participants
Number of participants with biosamples


Availability of data and biosamples