Individual Study / HEXA

KoGES_health examinees (HEXA) study

KoGES_health examinees (HEXA) study

Initiatives -
To investigate epidemiologic characteristics, genomic features, and gene-environment interactions of major chronic diseases including cancer in the Korean population. Constructing epidemiological infrastructure in order to examine environmental and genetic factors on common chronic diseases based on medical centers in urban cities.
Start Year
End Year
Supplementary Information
The Korean Genome and Epidemiology Study (KoGES) Consortium (6)
Visit HEXA


Investigators Contacts
  • Dr. Prof. Daehee Kang
    Seoul National University College of Medicine


Study design
Population cohort
Follow Up
Baseline(2004-2013)- 1st Follow up (2007 - 2016). Medical institutions have conducted active follow-up and recruit existing cohort members at 2-year intervals. To do so, they send an information leaflet by mail and make phone calls about the follow-up study. At follow-up, cohort members are examined by questionnaire, laboratory tests, and provide blood and urine samples.The principal purpose of passive follow-up is to ascertain cases by employing Korean health-related databases. In addition, the occurrence of cancer can be verified through National Cancer Registration data from the National Cancer Center (NCC). In cases of deaths during follow-up, the National Statistical Office confirms the cause of death.

Marker Paper

Health Examinees Study Group. The Health Examinees (HEXA) study: rationale, study design and baseline characteristics. Asian Pac J Cancer Prev. 2015;16(4):1591-7. doi: 10.7314/apjcp.2015.16.4.1591.

PUBMED 25743837


Sources of Recruitment
  • Individuals

Number of participants

Number of participants
Number of participants with biosamples
Supplementary Information
Individuals within the age range of 40-69 living in urban cities that have had health examination at medical centers


Availability of data and biosamples


Availability of access information

On the study website :