Synchros | HAPIEE

The Health, Alcohol and Psychosocial factors in Eastern Europe Study

Initiatives -

Start Year: 2002
Supplementary Information: Participants were assessed twice: baseline in 2002-2005 and re-examination in 2006-2008. Follow-up was for piloting the outcomes a) mortality from all causes and from CVD, and b) non-fatal cardiovascular events.

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Members

Investigators	Contacts
Prof Martin Bobak University College London Martin Bobak Title Prof Name Martin Bobak Email m.bobak@ucl.ac.uk Institution University College London Prof Sofia Malyutina Siberian Academy of the Russian Academy of Medical Sciences Sofia Malyutina Title Prof Name Sofia Malyutina Email smalyutina@hotmail.com Institution Siberian Academy of the Russian Academy of Medical Sciences	Prof Martin Bobak University College London Martin Bobak Title Prof Name Martin Bobak Email m.bobak@ucl.ac.uk Institution University College London

Design

Study design: Population cohort
Follow Up: Participants were assessed twice: baseline in 2002-2005 and re-examination in 2006-2008. Follow-up was for piloting the outcomes a) mortality from all causes and from CVD, and b) non-fatal cardiovascular events, since 2005.

Marker Paper

Peasey A, Bobak M, Kubinova R, Malyutina S, Pajak A, Tamosiunas A, Pikhart H, Nicholson A, Marmot M. Determinants of cardiovascular disease and other non-communicable diseases in Central and Eastern Europe: rationale and design of the HAPIEE study. BMC Public Health, 2006; 6: 255-65.

PUBMED 17049075

Recruitment

Sources of Recruitment

Individuals

Number of participants

Number of participants: 36,106
Number of participants with biosamples: 32,596

Access

General Information

Availability of data and biosamples

Data
Biosamples
Other

Yes

Not applicable

Don't know

Timeline

Populations

Selection Criteria

Minimum age

Maximum age

Newborns

Twins

Countries

Russian

Territory

Novosibirsk

Ethnic Origin

Health Status

Recruitment

Sources of recruitment

General population

General Population

Selected sample

Number of participants

Number of participants: 9,360
Number of participants with biosamples: 9,323

Data Collection Events

#	Name	Start	End
0	HAPIEE - Russia - Baseline HAPIEE - Russia - Baseline Data were collected by structured questionnaires and examination in clinic. The questionnaire covered information about health, self-rated health status, medical history, health behaviours, physical functioning, lifestyle, food frequency, socioeconomic circumstances, psychosocial factors, quality of life of retired persons, and psychosocial environment at work and effort-reward imbalance. The short examination included measurement of height, weight, trunk length, waist and hip circumference, blood pressure, lung function and cognitive function (memory, concentration and verbal skills). A sample of venous blood was also collected. Start Date 2002 End Date 2005 Data sources Questionnaires Cognitive measures Physical measures Biosamples Data sources - Biosamples Blood	2002	2005
1	HAPIEE - Russia - Re-examination HAPIEE - Russia - Re-examination Data was collected by face-to face Computer Assisted Personal Interview (CAPI). The main focus of the re-examination was healthy ageing and economic well-being. The ageing-related measures included cognitive functions, physical functioning, activities of daily living, instrumental activities of daily living, walk speed, chair rise and grip strength, quality of life and social participation. The economics measures included details on retirement, household composition, formal and informal household income, household wealth, and expectations of future pensions. Start Date 2006 End Date 2008 Data sources Questionnaires Cognitive measures Physical measures	2006	2008
2	HAPIEE - Russia - Mortality and cardiovascular events follow-up HAPIEE - Russia - Mortality and cardiovascular events follow-up To determine mortality, the death register developed by the Institute of Internal Medicine, which is based on data from medical death certificates, the Novosibirsk office of the State Statistical Bureau (Goscomstat) and from the population registration bureau (ZAGS) is used. Since 2011, individual mortality records based on death certificates in Russia are not available to researchers. Alternative methods have been used to collect mortality data since 2011 but the death rate in the Russian cohort since 2011 is underestimated. Efforts are currently under way to retrospectively collect data on missing deaths. In order to identify, confirm and validate incident non-fatal cardiovascular events, the same questionnaire is sent out every three years to identify the non-fatal cardiovascular events, which will be confirmed using discharge reports and hospital/medical records. Start Date 2005 End Date 2016 Data sources Questionnaires Administrative databases Data sources - Administrative databases Vital statistics databases	2005	2016

Selection Criteria

Minimum age

Maximum age

Newborns

Twins

Countries

Poland

Territory

Krakow

Ethnic Origin

Health Status

Recruitment

Sources of recruitment

General population

General Population

Selected sample

Number of participants

Number of participants: 10,728
Number of participants with biosamples: 9,274

Data Collection Events

#	Name	Start	End
0	HAPIEE - Poland - Baseline HAPIEE - Poland - Baseline Data were collected by structured questionnaires and examination in clinic. The questionnaire covered information about health, self-rated health status, medical history, health behaviours, physical functioning, lifestyle, food frequency, socioeconomic circumstances, psychosocial factors, quality of life of retired persons, and psychosocial environment at work and effort-reward imbalance. The short examination included measurement of height, weight, trunk length, waist and hip circumference, blood pressure, lung function and cognitive function (memory, concentration and verbal skills). A sample of venous blood was also collected. Start Date 2002 End Date 2005 Data sources Questionnaires Cognitive measures Physical measures Biosamples Data sources - Biosamples Blood	2002	2005
1	HAPIEE - Poland - Re-examination HAPIEE - Poland - Re-examination Data was collected by face-to face Computer Assisted Personal Interview (CAPI). The main focus of the re-examination was healthy ageing and economic well-being. The ageing-related measures included cognitive functions, physical functioning, activities of daily living, instrumental activities of daily living, walk speed, chair rise and grip strength, quality of life and social participation. The economics measures included details on retirement, household composition, formal and informal household income, household wealth, and expectations of future pensions. Start Date 2006 End Date 2008 Data sources Questionnaires Cognitive measures Physical measures	2006	2008
2	HAPIEE - Poland - Mortality and cardiovascular events follow-up HAPIEE - Poland - Mortality and cardiovascular events follow-up To determine mortality, the provincial death register covering the city of Krakow and surrounding area is used. In order to identify, confirm and validate incident non-fatal cardiovascular events, the same questionnaire is sent out every three years to identify the non-fatal cardiovascular events, which will be confirmed using discharge reports and hospital/medical records. Start Date 2005 End Date 2016 Data sources Questionnaires Administrative databases Data sources - Administrative databases Vital statistics databases	2005	2016

Selection Criteria

Minimum age

Maximum age

Newborns

Twins

Countries

Czech Republic

Territory

Havirov/Karvina, Hradec, Kralove, Jihlava, Kromeriz, Liberec and Usti nad Labem

Ethnic Origin

Health Status

Recruitment

Sources of recruitment

General population

General Population

Selected sample

Number of participants

Number of participants: 8,857
Number of participants with biosamples: 6,933

Data Collection Events

#	Name	Start	End
0	HAPIEE - Czech Republic - Baseline HAPIEE - Czech Republic - Baseline Data were collected by structured questionnaires and examination in clinic. The questionnaire covered information about health, self-rated health status, medical history, health behaviours, physical functioning, lifestyle, food frequency, socioeconomic circumstances, psychosocial factors, quality of life of retired persons, and psychosocial environment at work and effort-reward imbalance. The short examination included measurement of height, weight, trunk length, waist and hip circumference, blood pressure, lung function and cognitive function (memory, concentration and verbal skills). A sample of venous blood was also collected. Start Date 2002 End Date 2005 Data sources Questionnaires Cognitive measures Physical measures Biosamples Data sources - Biosamples Blood	2002	2005
1	HAPIEE - Czech Republic - Re-examination HAPIEE - Czech Republic - Re-examination Data was collected by face-to face Computer Assisted Personal Interview (CAPI). The main focus of the re-examination was healthy ageing and economic well-being. The ageing-related measures included cognitive functions, physical functioning, activities of daily living, instrumental activities of daily living, walk speed, chair rise and grip strength, quality of life and social participation. The economics measures included details on retirement, household composition, formal and informal household income, household wealth, and expectations of future pensions. Start Date 2006 End Date 2008 Data sources Questionnaires Cognitive measures Physical measures	2006	2008
2	HAPIEE - Czech Republic - Mortality and cardiovascular events follow-up HAPIEE - Czech Republic - Mortality and cardiovascular events follow-up To determine mortality, the national death register is used. In order to identify, confirm and validate incident non-fatal cardiovascular events, the same questionnaire is sent out every three years to identify the non-fatal cardiovascular events, which will be confirmed using discharge reports and hospital/medical records. Start Date 2005 End Date 2016 Data sources Questionnaires Administrative databases Data sources - Administrative databases Vital statistics databases	2005	2016

Selection Criteria

Minimum age

Maximum age

Newborns

Twins

Countries

Lithuania

Territory

Kaunas

Ethnic Origin

Health Status

Recruitment

Sources of recruitment

General population

General Population

Selected sample

Number of participants

Number of participants: 7,161
Number of participants with biosamples: 7,066

Data Collection Events

#	Name	Start	End
0	HAPIEE - Lithuania - Baseline HAPIEE - Lithuania - Baseline Baseline data collection and collection of additional data on healthy ageing and economic well-being was collected simultaneously. Data were collected by structured questionnaires and examination in clinic. The questionnaire covered information about health, self-rated health status, medical history, health behaviours, physical functioning, lifestyle, food frequency, socioeconomic circumstances, psychosocial factors, quality of life of retired persons, and psychosocial environment at work and effort-reward imbalance. The ageing-related measures included cognitive functions, physical functioning, activities of daily living, instrumental activities of daily living, walk speed, chair rise and grip strength, quality of life and social participation. The economics measures included details on retirement, household composition, formal and informal household income, household wealth, and expectations of future pensions. The short examination included measurement of height, weight, trunk length, waist and hip circumference, blood pressure, lung function and cognitive function (memory, concentration and verbal skills). A sample of venous blood was also collected. Start Date 2005 End Date 2008 Data sources Questionnaires Cognitive measures Physical measures Biosamples Data sources - Biosamples Blood	2005	2008
1	HAPIEE - Lithuania - Mortality and cardiovascular events follow-up HAPIEE - Lithuania - Mortality and cardiovascular events follow-up To determine mortality, the Kaunas regional mortality register is used. In order to identify, confirm and validate incident non-fatal cardiovascular events, the same questionnaire is sent out every three years to identify the non-fatal cardiovascular events, which will be confirmed using discharge reports and hospital/medical records. Start Date 2005 End Date 2016 Data sources Questionnaires Administrative databases Data sources - Administrative databases Vital statistics databases	2005	2016
2	HAPIEE - Lithuania - Re-examination HAPIEE - Lithuania - Re-examination Data was collected by face-to face Computer Assisted Personal Interview (CAPI). The main focus of the re-examination was healthy ageing and economic well-being. The ageing-related measures included cognitive functions, physical functioning, activities of daily living, instrumental activities of daily living, walk speed, chair rise and grip strength, quality of life and social participation. The economics measures included details on retirement, household composition, formal and informal household income, household wealth, and expectations of future pensions. Start Date 2006 End Date 2008 Data sources Questionnaires Physical measures	2006	2008

Individual Study / HAPIEE

The Health, Alcohol and Psychosocial factors in Eastern Europe Study

Members

Design

Marker Paper

Recruitment

Number of participants

Access

Timeline

Populations

Selection Criteria

Recruitment

Number of participants

Data Collection Events

Selection Criteria

Recruitment

Number of participants

Data Collection Events

Selection Criteria

Recruitment

Number of participants

Data Collection Events

Selection Criteria

Recruitment

Number of participants

Data Collection Events

Variables Classifications

Individual Study / HAPIEE

The Health, Alcohol and Psychosocial factors in Eastern Europe Study

Members

Martin Bobak

Sofia Malyutina

Martin Bobak

Design

Marker Paper

Recruitment

Number of participants

Access

Timeline

Populations

Selection Criteria

Recruitment

Number of participants

Data Collection Events

HAPIEE - Russia - Baseline

HAPIEE - Russia - Re-examination

HAPIEE - Russia - Mortality and cardiovascular events follow-up

Selection Criteria

Recruitment

Number of participants

Data Collection Events

HAPIEE - Poland - Baseline

HAPIEE - Poland - Re-examination

HAPIEE - Poland - Mortality and cardiovascular events follow-up

Selection Criteria

Recruitment

Number of participants

Data Collection Events

HAPIEE - Czech Republic - Baseline

HAPIEE - Czech Republic - Re-examination

HAPIEE - Czech Republic - Mortality and cardiovascular events follow-up

Selection Criteria

Recruitment

Number of participants

Data Collection Events

HAPIEE - Lithuania - Baseline

HAPIEE - Lithuania - Mortality and cardiovascular events follow-up

HAPIEE - Lithuania - Re-examination

Variables Classifications