Individual Study / GHS

Gutenberg Health Study

Gutenberg Health Study

GHS logo
Initiatives -
* The Gutenberg Health Study is a large-scale prospective and population-based study. The general health and particularly the cardiovascular and vascular health in the city of Mainz and the district of Mainz-Bingen is investigated. Cancer, eye diseases, diseases of the immune system, metabolic and mental diseases are examined as part of this study as well. * The main goals of the ophthalmological branch of GHS are determination of the prevalence and incidence of major ocular risk factors and diseases, exploring the genetic determinants and assessing complex interdisciplinary associations. ****
Start Year
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Investigators Contacts
  • Dr. Alireza Mirshahi
    University Medical Center of the Johannes Gutenberg University Mainz


Study design
Population cohort
Follow Up
Participants was performed between 2007 and 2012. A 2.5 year follow-up conducted as a telephone interview started in 2009. Since 2012, the 5-year follow up has been achieved through record linkage, including a second visit at the study centre with extensive medical examination and re-sampling of the biomaterial which is ongoing.

Marker Paper

Mirshahi A, Ponto KA, Höhn R, Wild PS, Pfeiffer N. Ophthalmologische Aspekte der Gutenberg Gesundheitsstudie: Eine interdisziplinäre prospektive populationsbasierte Kohortenstudie [Ophthalmological aspects of the Gutenberg Health Study (GHS): an interdisciplinary prospective population-based cohort study]. Ophthalmologe. 2013 Mar;110(3):210-7. German. doi: 10.1007/s00347-012-2666-0.

PUBMED 23504093


Sources of Recruitment
  • Individuals

Number of participants

Number of participants
Number of participants with biosamples
Supplementary Information
Aged 35-74 years old (Rhine-Main area of Western Germany)


Availability of data and biosamples