Evaluating More Naturalistic Outcome Measures: A 1-year Smartphone Study in Multiple Sclerosis
Initiatives
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In this cohort of individuals with and without multiple sclerosis (MS) some of the novel approaches that smartphones provide to monitor patients with chronic neurologicdisorders in their natural setting was illustrate.
Note: All published information has been collected from the article referenced in the Marker Paper box below. Therefore, there may be variations with more advanced versions of the study.
- Start Year
- 2012
- Funding
- This study was funded by Vertex Pharmaceuticals Incorporated
Design
- Study design
- Patients' cohort
Marker Paper
Bove R, White CC, Giovannoni G, et al. Evaluating more naturalistic outcome measures: A 1-year smartphone study in multiple sclerosis. Neurol Neuroimmunol Neuroinflamm. 2015;2(6):e162. Published 2015 Oct 15. doi:10.1212/NXI.0000000000000162
PUBMED 26516627
Recruitment
- Sources of Recruitment
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- Other : Pairs consisting of 1 patient with demyelinating disease and 1 healthy cohabitant
Number of participants
- Number of participants
- 76
- Number of participants with biosamples
- Supplementary Information
- 38 participant pairs (MS and cohabitant)
Access
Availability of data and biosamples
| Data | |
| Biosamples | |
| Other |
Timeline
Patients with and without multiple sclerosis (MS)
Pairs consisting of 1 patient with demyelinating disease and 1 healthy cohabitant, all aged 18–55years, were recruited at the Partners MS Center, a large referralclinical center in the northeastern United States.
Selection Criteria
- Minimum age
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18
- Maximum age
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55
- Newborns
- Twins
- Countries
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- United States of America
- Ethnic Origin
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- Health Status
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- Patients with multiple sclerosis (MS)
Recruitment
- Sources of recruitment
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- Specific population
- Specific Population
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- Clinic patients
Number of participants
- Number of participants
- 76
- Number of participants with biosamples
- Supplementary Information
- Thirty-eight participant pairs (MS and cohabitant) aged 18–55 years participated in thestudy.
Data Collection Event
Each participant received an Android HTC Sensation4G smartphone as well as a free cellular phone service plan for theduration of the study.A custom application suite consisting of 19 tests was designedto (1) assess participant performance (color vision, attention, dex-terity, and cognition), and (2) elicit patient-reported outcomes(PROs; fatigue, mood, and QOL).
- Start Date
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2012-05
- End Date
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2014-01
- Data sources
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Mobile data collection
- Smartphone
- Smartphone apps
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Mobile data collection