Medication Adherence Assessment: High Accuracy of the New Ingestible Sensor System in Kidney Transplants
Initiatives
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This open-label single-arm exploratory study evaluated the accuracy of the Ingestible Sensor System (ISS), a novel technology for directly assessing the ingestion of oral medications and treatment adherence.
Note: All published information has been collected from the article referenced in the Marker Paper box below. Therefore, there may be variations with more advanced versions of the study.
- Start Year
- 2011
- End Year
- 2011
- Funding
- The study was cofunded by Novartis and Proteus.
Design
- Study design
- Clinical trial cohort
Marker Paper
Eisenberger U, Wüthrich RP, Bock A, et al. Medication adherence assessment: high accuracy of the new Ingestible Sensor System in kidney transplants. Transplantation. 2013;96(3):245‐250. doi:10.1097/TP.0b013e31829b7571
PUBMED 23823651
Recruitment
- Sources of Recruitment
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- Individuals
Number of participants
- Number of participants
- 20
- Number of participants with biosamples
Access
Availability of data and biosamples
| Data | |
| Biosamples | |
| Other |
Timeline
Participants were stable adults who had undergone kidney transplants
Twenty patients participated in this 12-week uncontrolled pilot study. Patients were in majority Caucasians (19 of 20), males (15 of 20), and 51.7±8.8 years old (mean±SD; range 35–68) and had a body weight of 81.8±12.7 kg (range, 54.5–105.4). They were in stable condition after an average of 6.0±5.0 years after renal transplantation (range, 1–19 years) and taking ECMPS or mycophenolate mofetil in combination with cyclosporine (7 patients), tacrolimus (11 patients), sirolimus (1 patient), or everolimus (1 patient). Three (15%) patients had a second transplant.
Selection Criteria
- Newborns
- Twins
- Countries
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- Switzerland
- Ethnic Origin
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- Health Status
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- kidney transplants
Recruitment
- Sources of recruitment
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- General population
Number of participants
- Number of participants
- 20
- Number of participants with biosamples
Data Collection Event
This open-label single-arm exploratory study evaluated the accuracy of the Ingestible Sensor System (ISS), a novel technology for directly assessing the ingestion of oral medications and treatment adherence.
- Start Date
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2011-05
- End Date
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2011-11
- Data sources
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Smart sensors
- Ingestible sensors
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Smart sensors