Electroconvulsive therapy-induced brain plasticity determines therapeutic outcome in mood disorders (The GEMRIC centers in Lausanne, Switzerland and Berlin, Germany)
Initiatives
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"This study shows differential, highly specific, spatially distributed effects of ECT on regional brain structure in two populations: patients with unipolar or bipolar
disorder. Unipolar and bipolar disorders respond differentially to ECT and the associated local brain-volume changes, which occur in areas previously associated with these diseases, correlate with symptom severity and the therapeutic effect. The evidence demonstrate that electrophysical therapeutic effects, although applied generally, take on regional significance through interactions with brain pathophysiology."
Visit Dukart_Proc Natl Acad Sci USA_2014
| Investigators | Contacts |
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Design
- Study design
- Patients' cohort
Marker Paper
Dukart J, Regen F, Kherif F, et al. Electroconvulsive therapy-induced brain plasticity determines therapeutic outcome in mood disorders. Proc Natl Acad Sci USA. 2014;111(3):1156-1161. doi:10.1073/pnas.1321399111
PUBMED 24379394
Recruitment
- Sources of Recruitment
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- Individuals
Number of participants
- Number of participants
- 10
- Number of participants with biosamples
Access
Availability of data and biosamples
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| Biosamples | |
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Availability of access information
On the study website : https://mmiv.no/gemric/