Individual Study / DMS

De Maastricht Studie

De Maastricht Studie

Initiatives -
It aims to identify determinants of the development and progression of * T2DM; * its classic complications(cardiovascular disease, retinopathy, neuropathy and nephropathy); * its emerging comorbidities, such as cognitive decline, depression, and gastrointestinal, musculoskeletal and respiratory diseases. In addition, the impact of this clustering of comorbidities on quality of life and use of health care resources will be defined.
Start Year
2010
End Year
2017
Funding
European Regional Development Fund as part of OP-ZUID, the province of Limburg, the department of Economic Affairs of the Netherlands (grant 31O.041), Stichting the Weijerhorst, the Pearl String Initiative Diabetes, the Cardiovascular Center Maastricht, Cardiovascular Research Institute Maastricht (CARIM), School for Nutrition, Toxicology and Metabolism (NUTRIM), Stichting Annadal, Health Foundation Limburg and by unrestricted grants from Janssen, NovoNordisk and Sanofi.
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Members

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Investigators Contacts
  • Dr. Professor Miranda T. Schram
    Maastricht University Medical Center

Design

Study design
Patients' cohort
Follow Up
Annual follow-up on disease incidence and mortality. Extensive medical examinations at the start of the study and after 5 years. Annual follow-up of disease incidence and mortality is in progress, comprising (1) collection of information from participants using an annual follow-up questionnaire specifically directed to chronic diseases that occurred in the past year; (2) linking of participant data to hospital and pharmacy records; and (3) collection of mortality data through existing up-to-date databases from Statistics Netherlands (CBS).

Marker Paper

Schram MT, Sep SJ, van der Kallen CJ, Dagnelie PC, Koster A, Schaper N, Henry RM, Stehouwer CD. The Maastricht Study: an extensive phenotyping study on determinants of type 2 diabetes, its complications and its comorbidities. Eur J Epidemiol. 2014 Jun;29(6):439-51. doi: 10.1007/s10654-014-9889-0. Epub 2014 Apr 23.

PUBMED 24756374

Recruitment

Sources of Recruitment
  • Individuals

Number of participants

Number of participants
10,000
Number of participants with biosamples
Supplementary Information
T2DM individuals

Access

Availability of data and biosamples

Data
Biosamples
Other

Availability of access information

On the study website : https://www.demaastrichtstudie.nl/

By contacting the study representative