Individual Study / DINE

Developmental Impact of Nicu Expousures

Developmental Impact of Nicu Expousures

Initiatives -
The study is focused on neonatal intensive care unit (NICU).The objectives of the study are: 1. (UG3) will use existing NICU datasets and biorepositories to determine specific routes and sources of phthalate exposure. 2. Measure the impact of NICU-based phthalate exposure on multisystem health outcomes at ages 3-10. (UG3/UH3) examines associations among urine biomarkers of NICU phthalate exposure and childhood measures of pulmonary function, cognitive, motor, and behavioral performance, growth and pubertal development. 3. Determine the impact of and interactions among early childhood phthalate, manganese, lead and stress exposures on neurodevelopmental outcomes in preterm and term children. (UH3) uses tooth, hair and saliva biomarkers of exposures to investigate neurobehavioral development in children born preterm and at term.
Start Year
2016
End Year
2023
Funding
National Institutes of Health (NIH)
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Members

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Investigators Contacts
  • MD. Prof. Judy Lynn Aschner
    Albert Einstein College of Medicine

Design

Study design
Population cohort

Marker Paper

Zhang X, Spear E, Gennings C, Curtin PC, Just AC, Bragg JB, Stroustrup A. The association of prenatal exposure to intensive traffic with early preterm infant neurobehavioral development as reflected by the NICU Network Neurobehavioral Scale (NNNS). Environ Res. 2020 Apr;183:109204. doi: 10.1016/j.envres.2020.109204. Epub 2020 Jan 31.

PUBMED 32311904

Recruitment

Sources of Recruitment
  • Individuals

Number of participants

Number of participants
240
Number of participants with biosamples

Access

Availability of data and biosamples

Data
Biosamples
Other