Individual Study / CPS-II

The American Cancer Society Cancer Prevention Study II

The American Cancer Society Cancer Prevention Study II

Initiatives -
Discovering factors that contribute to variability in cancer risk in human populations. To examine the effect of cigarette smoking and a wide range of potential exposures on death rates from cancer and other diseases
Start Year
End Year
American Cancer Society
Visit CPS-II


Investigators Contacts
  • Dr. Alpa V. Patel
    American Cancer Society
  • Dr. Eric Jacobs
    American Cancer Society


Study design
Population cohort
Follow Up
Mortality follow-up: every second year, the volunteer researchers were given lists of persons whom they had enrolled and asked to check whether they were alive or dead, and if dead, the date and place of death.

Marker Paper

Calle EE, Rodriguez C, Jacobs EJ, Almon ML, Chao A, McCullough ML, Feigelson HS, Thun MJ. The American Cancer Society Cancer Prevention Study II Nutrition Cohort: rationale, study design, and baseline characteristics. Cancer. 2002 Jan 15;94(2):500-11. doi: 10.1002/cncr.10197. Corrected and republished in: Cancer. 2002 May 1;94(9):2490-501. PMID: 11900235.

PUBMED 11900235


Sources of Recruitment
  • Individuals

Number of participants

Number of participants
Number of participants with biosamples
Supplementary Information
The cohort includes over 84,000 men and 97,000 women.Approximately 77,000 volunteers for the American Cancer Society recruited participants into the study in all 50 states, the District of Columbia, and Puerto Rico


Availability of data and biosamples


Availability of access information

On the study website :