Individual Study / COGFAST-UK

Cognitive Function After Stroke

Cognitive Function After Stroke

Initiatives -
To examine whether modifiable risk factors known at the time of the index stroke would be useful in predicting dementia outcomes. *Note: All published information has been collected from the article referenced in the Marker Paper box below. Therefore, there may be variations with more advanced versions of the study.*
Start Year
2002
End Year
2012
Funding
UK Medical Research Council (MRC, G0500247); Newcastle Centre for Brain Ageing and Vitality (BBSRC, EPSRC, ESRC and MRC, LLHW); and the Alzheimer's Research Trust (UK).

Members

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Investigators Contacts
  • Dr. Rajesh Kalaria
    Newcastle University

Design

Study design
Patients' cohort
Follow Up
Longitudinal study 3 months after stroke. At baseline none of the patients had dementia. Assessed annually for cognition and development of incident dementia over up to 8 years of follow-up.

Marker Paper

Allan, L. M., Rowan, E. N., Firbank, M. J., Thomas, A. J., Parry, S. W., Polvikoski, T. M., O'Brien, J. T., & Kalaria, R. N. (2011). Long term incidence of dementia, predictors of mortality and pathological diagnosis in older stroke survivors. Brain : a journal of neurology, 134(Pt 12), 3716–3727. https://doi.org/10.1093/brain/awr273

Recruitment

Sources of Recruitment
  • Individuals

Number of participants

Number of participants
355
Number of participants with biosamples
Supplementary Information
Over 75 years old

Access

Availability of data and biosamples

Data
Biosamples
Other