Individual Study / CKB

China Kadoorie Biobank

China Kadoorie Biobank

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Initiatives -
To investigate the main genetic and environmental causes of common chronic diseases in the Chinese population. Large blood-based prospective cohort studies can provide reliable assessment of the complex interplay of lifestyle, environmental, and genetic susceptibility as causes of chronic disease. The main objectives of the study are: 1. To assess reliably the effects of both established and emerging risk factors for many diseases, not only overall but also under various circumstances (e.g. at different ages and at different levels of other risk factors); 2. To determine the complex interplay between genes and environmental factors and between different genes on the risks of common chronic diseases. ** General Enquiries Email: ckbiobank@ndph.ox.ac.uk **
Start Year
2004
Funding
It was established with funding support to University of Oxford’s Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU) from the Kadoorie Charitable Foundation (KCF) in Hong Kong. The long-term continuation of the study is supported by the Wellcome Trust, with further support in China from the Chinese Natural Science Foundation and Chinese Ministry of Science and Technology. The UK Medical Research Council (MRC), British Heart Foundation (BHF) and Cancer Research UK (CRUK) also provide core funding to CTSU for the project.
Supplementary Information
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Members

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Investigators Contacts
  • Dr. Prof. Liming Li
    Peking University Health Science Center
  • Dr. Prof. Chen Zhengming
    China Programs at the Oxford University’s Clinical Trial Service Unit and Epidemiological Studies Unit (CTSU)

Design

Study design
Population cohort
Follow Up
All the participants are now being closely monitored for death and other health-related outcomes through linkage with established registries and health insurance databases in the study areas. Every few years, periodic re-surveys are also to be conducted in about 25,000 surviving participants, with a repeat interview, measurements and blood collection (as in the baseline survey) to help assess changes of risk exposures in the study population.
Supplementary Information

Marker Paper

Chen Z, Chen J, Collins R, et al. China Kadoorie Biobank of 0.5 million people: survey methods, baseline characteristics and long-term follow-up. Int J Epidemiol. 2011;40(6):1652-1666. doi:10.1093/ije/dyr120

PUBMED 22158673

Recruitment

Sources of Recruitment
  • Individuals

Number of participants

Number of participants
512,891
Number of participants with biosamples

Access

Availability of data and biosamples

Data
Biosamples
Other

Availability of access information

On the study website : https://www.ckbiobank.org/site/