Individual Study / CHECK

Cohort Hip and Cohort Knee
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Cohort Hip and Cohort Knee

Initiatives -
To study the course of complaints, the mechanisms that cause joint damage, and to identify markers for diagnosis and prognosis, as well as to identify prognostic factors that predict and explain the course of osteoarthritis (OA). ** Access to data contact: checkreu@umcutrecht.nl **
Start Year
2002
End Year
2015
Funding
Dutch Arthritis Foundation
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Members

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Investigators Contacts
  • Dr Janet Wesseling
    University Medical Centre Utrecht

Design

Study design
Patients' cohort
Follow Up
Participants with mild symptoms visited the research centre at years 0, 2, 5, 8 and 10 (variable visiting group) and participants with more serious symptoms visited the research centre each year (annual visiting group). For 10 years after baseline examinations every year, that included a questionnaire and clinical data; once every 2-3 years the examinations also included X ray, blood and urine collection.

Marker Paper

Wesseling J, Boers M, Viergever MA, Hilberdink WK, Lafeber FP, Dekker J, Bijlsma JW. Cohort Profile: Cohort Hip and Cohort Knee (CHECK) study. Int J Epidemiol. 2016 Feb;45(1):36-44. doi: 10.1093/ije/dyu177. Epub 2014 Aug 29.

PUBMED 25172137

Recruitment

Sources of Recruitment
  • Individuals

Number of participants

Number of participants
1,002
Number of participants with biosamples
Supplementary Information
Participants with symptomatic osteoarthritis of hip and/or knee

Access

Availability of data and biosamples

Data
Biosamples
Other

Availability of access information

On the study website : https://www.check-onderzoek.nl/

Yes
No
Not applicable
Don't know