Individual Study / CC75C

Cambridge City over-75s Cohort study

Cambridge City over-75s Cohort study

Initiatives -
The design started as a mechanism to detect people in the earliest stages of dementia, not yet perceived by their families, who could then be followed and in whom different patterns of care might be investigated. The focus in later years shifted to quality of life issues of “older old” people near the end of life.
Start Year
Visit CC75C


Investigators Contacts
  • Dr. Prof. Stephen Barclay
    University of Cambridge
  • Prof. Carol Brayne
    University of Cambridge


Study design
Population cohort
Follow Up
Each follow-up survey has included the Cambridge Cognitive Examination (CAMCOG). Sub-samples have had detailed psychiatric assessment using the Cambridge Diagnostic Examination for the Elderly (CAMDEX) interview, detailed neuropsychological assessment and additional tests. Longitudinal data are also available on socio-demographic variables (e.g. change of residence, household structure, change in marital status, social contact), activities of daily living, use of health and social services, health problems and medication, self-rated health and subjective well-being.

Marker Paper

Fleming J, Zhao E, O'Connor DW, Pollitt PA, Brayne C. Cohort profile: the Cambridge City over-75s Cohort (CC75C). Int J Epidemiol. 2007 Feb;36(1):40-6. doi: 10.1093/ije/dyl293.

PUBMED 17510074


Sources of Recruitment
  • Individuals

Number of participants

Number of participants
Number of participants with biosamples


Availability of data and biosamples