Cognition and Affect after Stroke: Prospective Evaluation of Risks
Initiatives
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* To examine whether stroke-specific (e.g. lesion location, volume, type, severity), cerebrovascular and neurodegenerative (e.g. white matter changes, atrophy, microbleeds, perivascular spaces), inflammatory, endothelial, and (epi)genetic markers are associated with cognitive impairment, post-stroke depression, and post-stroke apathy, and whether they predict their course over 12 months.
* The secondary aims are to investigate how the above-mentioned markers interact with each other, and to determine if patients with apathy and depression after stroke differ in pathogenesis, course, and outcome (e.g. functional outcome, neurocognitive performance, quality of life).
*Note: All published information has been collected from the article referenced in the Marker Paper box below. Therefore, there may be variations with more advanced versions of the study.*
- Start Year
- 2013
- End Year
- 2016
- Funding
- his project was funded by Maastricht University, Health Foundation Limburg, and the Adriana van Rinsum-Ponsen Stichting.
| Investigators | Contacts |
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Design
- Study design
- Patients' cohort
- Follow Up
- 6m after baseline (9m after stroke), 12m after baseline (15m after stroke)
Marker Paper
Douven, E., Schievink, S., Verhey, F.R.J. et al. The Cognition and Affect after Stroke - a Prospective Evaluation of Risks (CASPER) study: rationale and design. BMC Neurol 16, 65 (2016). https://doi.org/10.1186/s12883-016-0588-1
Recruitment
- Sources of Recruitment
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- Individuals
Number of participants
- Number of participants
- 250
- Number of participants with biosamples
- Supplementary Information
- Over 40 years old
Access
Availability of data and biosamples
| Data | |
| Biosamples | |
| Other |