Individual Study / Betula - Aging, memory and dementia

Betula - Aging, memory and dementia

Betula - Aging, memory and dementia

Initiatives -
Population based (25–100 yrs.), started in 1988, the seventh wave is ongoing. 10400 test sessions, with ~5850 longitudinal observations. All were healthy and non-demented at baseline, but more than 400 have developed some form of dementia. Very comprehensive examinations on health, biomarkers, genotyping, neuropsychology and brain imaging. Time points five and six are part of Lifebrain.
Start Year
1988
End Year
2004
Visit Betula - Aging, memory and dementia

Members

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Investigators Contacts
  • Dr. Prof. Lars Nyberg
    Umeå Center for Functional Brain Imaging (UFBI)
  • Mikael Stiernstedt
    Umea University

Design

Study design
Population cohort
Follow Up
The participants of the project have was tested, interviewed and examined medically at six occasions (1988-1990, 1993-1995, 1998-2000, 2003-2005, 2008-2010 and 2013-2014)

Marker Paper

Rönnlund M, Sundström A, Adolfsson R, et al. Subjective memory impairment in older adults predicts future dementia independent of baseline memory performance: Evidence from the Betula prospective cohort study.Alzheimers Dement. 2015;11(11):1385-1392. doi:10.1016/j.jalz.2014.11.006

Recruitment

Sources of Recruitment
  • Individuals

Number of participants

Number of participants
376
Number of participants with biosamples
Supplementary Information
Aged over 65 years

Access

Availability of data and biosamples

Data
Biosamples
Other