Effects of electroconvulsive therapy on brain functional activation and connectivity in depression (The GEMRIC Cleveland, OH, USA center)
Initiatives
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Past neuroimaging work has suggested that increased activation to cognitive and emotional tasks and decreased connectivity in frontal regions are related to cognitive inefficiency in depression; normalization of these relationships has been associated with successful treatment. The present study investigated brain function before and after electroconvulsive therapy (ECT) in patients with major depressive disorder (MDD) and demonstrated the effect of treatment on cortical activation patterns.
Visit Beal_J ECT_2012
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Design
- Study design
- Patients' cohort
- Follow Up
- Within 1 week before and 1 to 3 weeks after ECT
Marker Paper
Beall EB, Malone DA, Dale RM, et al. Effects of electroconvulsive therapy on brain functional activation and connectivity in depression. J ECT. 2012;28(4):234-241. doi: 10.1097/YCT.0b013e31825ebcc7
PUBMED 22820953
Recruitment
- Sources of Recruitment
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- Individuals
Number of participants
- Number of participants
- 6
- Number of participants with biosamples
Access
Availability of data and biosamples
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| Biosamples | |
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Availability of access information
On the study website : https://mmiv.no/gemric/