Individual Study / Beal_J ECT_2012

Effects of electroconvulsive therapy on brain functional activation and connectivity in depression (The GEMRIC Cleveland, OH, USA center)

Effects of electroconvulsive therapy on brain functional activation and connectivity in depression (The GEMRIC Cleveland, OH, USA center)

Initiatives -
Past neuroimaging work has suggested that increased activation to cognitive and emotional tasks and decreased connectivity in frontal regions are related to cognitive inefficiency in depression; normalization of these relationships has been associated with successful treatment. The present study investigated brain function before and after electroconvulsive therapy (ECT) in patients with major depressive disorder (MDD) and demonstrated the effect of treatment on cortical activation patterns.
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Investigators Contacts
  • Dr. Erik Beall
    Cleveland Clinic

Design

Study design
Patients' cohort
Follow Up
Within 1 week before and 1 to 3 weeks after ECT

Marker Paper

Beall EB, Malone DA, Dale RM, et al. Effects of electroconvulsive therapy on brain functional activation and connectivity in depression. J ECT. 2012;28(4):234-241. doi: 10.1097/YCT.0b013e31825ebcc7

PUBMED 22820953

Recruitment

Sources of Recruitment
  • Individuals

Number of participants

Number of participants
6
Number of participants with biosamples

Access

Availability of data and biosamples

Data
Biosamples
Other

Availability of access information

On the study website : https://mmiv.no/gemric/