Individual Study / ATBC

Alpha-Tocopherol, BetaCarotene Cancer Prevention Study

Alpha-Tocopherol, BetaCarotene Cancer Prevention Study

Initiatives -
The main purposes of the ATBC cohort follow-up are: * To use the existing risk factor data and biological specimens (i.e., serum, whole blood, DNA, red blood cells, and toenails) to test hypotheses relevant to cancer etiology, survival, early detection, and prevention. * To determine whether certain vitamin supplements would prevent lung cancer and other cancers
Start Year
1985
End Year
2013
Funding
National Cancer Institute
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Members

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Investigators Contacts
  • Dr Christian Abnet
    National Institutes of Health
  • Dr Satu Männistö
    National Institute for Health and Welfare
  • MD. Prof Demetrius Albanes
    State University of New York

Design

Study design
Clinical trial cohort
Follow Up
Participants were followed after the trial ended using data from the national registries in Finland in order to evaluate the long-term effects of the vitamins on cancer incidence, and overall and cause-specific mortality.

Marker Paper

The alpha-tocopherol, beta-carotene lung cancer prevention study: design, methods, participant characteristics, and compliance. The ATBC Cancer Prevention Study Group. Ann Epidemiol. 1994 Jan;4(1):1-10. doi: 10.1016/1047-2797(94)90036-1.

PUBMED 8205268

Recruitment

Sources of Recruitment
  • Individuals

Number of participants

Number of participants
29,133
Number of participants with biosamples
Supplementary Information
Male smokers (Finland) aged 50 to 69 years

Access

Availability of data and biosamples

Data
Biosamples
Other