Individual Study / Arean et al.; J Med Internet Res. 2016

The Use and Effectiveness of Mobile Apps for Depression: Results From a Fully Remote Clinical Trial

The Use and Effectiveness of Mobile Apps for Depression: Results From a Fully Remote Clinical Trial

Initiatives -
The objective of our study was to document and compare use patterns and clinical outcomes across the United States between 3 different self-guided mobile apps for depression. Note: All published information has been collected from the article referenced in the Marker Paper box below. Therefore, there may be variations with more advanced versions of the study.
Start Year
2014
Funding
Support for this research was provided by the National Institute of Mental Health (PAA R34-MH100466, T32MH0182607, K24MH074717). PAA had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.

Design

Study design
Clinical trial cohort

Marker Paper

Arean PA, Hallgren KA, Jordan JT, et al. The Use and Effectiveness of Mobile Apps for Depression: Results From a Fully Remote Clinical Trial. J Med Internet Res. 2016;18(12):e330. Published 2016 Dec 20. doi:10.2196/jmir.6482

PUBMED 27998876

Recruitment

Sources of Recruitment
  • Individuals

Number of participants

Number of participants
626
Number of participants with biosamples

Access

Availability of data and biosamples

Data
Biosamples
Other

Timeline

Population

Participants were recruited through Web-based advertisements and social media and were randomly assigned to 1 of 3 mood apps. Treatment and assessment were conducted remotely on each participant's smartphone or tablet with minimal contact with study staff. We enrolled 626 English-speaking adults (≥18 years old) with mild to moderate depression as determined by a 9-item Patient Health Questionnaire (PHQ-9) score ≥5, or if their score on item 10 was ≥2.
Selection Criteria
Minimum age
18
Newborns
Twins
Countries
  • United States of America
Ethnic Origin
Health Status
  • moderate depression

Recruitment

Sources of recruitment
  • General population

Number of participants

Number of participants
626
Number of participants with biosamples
Data Collection Event
The apps were Project: EVO, a cognitive training app theorized to mitigate depressive symptoms by improving cognitive control, iPST, an app based on an evidence-based psychotherapy for depression, and Health Tips, a treatment control. Outcomes were scores on the PHQ-9 and the Sheehan Disability Scale.
Start Date
2014-08
Data sources
  • Mobile data collection
    • Smartphone
    • Smartphone apps