Individual Study / ALSPAC G2

The second generation of The Avon Longitudinal Study of Parents and Children

The second generation of The Avon Longitudinal Study of Parents and Children

Initiatives -
To provide a unique multi-generational family study and to be a resource for interna-tional researchers to explore the environmental, socioeconomic, lifestyle, physiological, metabolic, genomic and epigenomiccontributions to health and development across the lifecourse and across generations. **alspac-exec@bristol.ac.uk**
Start Year
2012
End Year
2024
Funding
ALSPAC receives core-funding from the University of Bristol, Wellcome Trust and MRC (102215/2/13/2). This study wasGrant information:supported by the National Institute for Health Research NIHR Biomedical Research Centre at the University Hospitals Bristol NHS National HealthService Foundation Trust and the University of Bristol, the US National Institute for Health (grant R01 DK10324), and the European ResearchCouncil under the European Union’s Seventh Framework Programme (grant FP/2007-2013) / European Research Council ERC Grant Agreements(Grant grants refs 758813 MHINT and 669545 DevelopObese). Medtronic Limited provided support for the pilot study of continuous glucosemonitoring. The Wellcome Trust Institutional Strategic Support Fund and Elizabeth Blackwell Institute at the University of Bristol provided supportfor the novel diet methods pilot study
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Members

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Investigators Contacts
  • Melanie Lewcock
    University of Bristol
  • Dr. Professor Deborah A Lawlor
    University of Bristol

Design

Study design
Population cohort
Follow Up
We currently have protocols for data collection (on both parents (ALSPAC-G1) and their offspring (ALSPAC-G2)) for early pregnancy (up to 20 completed weeks of gestation), late pregnancy (≥28 weeks gestation), first 7–15 days, 6-months, 12 months, annually up to 7 years and then at 9 and 11 years. Our current plans are to extend this with protocols for data collection every 2 years up to the age of 21 over the next 5-years.

Marker Paper

Lawlor DA, Lewcock M, Rena-Jones L, Rollings C, Yip V, Smith D, Pearson RM, Johnson L, Millard LAC, Patel N, Skinner A, Tilling K; ALSPAC Executive. The second generation of The Avon Longitudinal Study of Parents and Children (ALSPAC-G2): a cohort profile. Wellcome Open Res. 2019 Feb 20;4:36. doi: 10.12688/wellcomeopenres.15087.2.

PUBMED 31984238

Recruitment

Sources of Recruitment
  • Families

Number of participants

Number of participants
810
Number of participants with biosamples
Supplementary Information
Children of ALSPAC-G1 (and grandchildren of ALSPAC-G0).

Access

Availability of data and biosamples

Data
Biosamples
Other

Availability of access information

On the study website : http://www.bristol.ac.uk/alspac/

By contacting the study representative