Individual Study / ALSPAC

Avon Longitudinal Study of Parents and Children

Avon Longitudinal Study of Parents and Children

Initiatives -
ALSPAC is a transgenerational prospective observational study investigating influences on health and development across the life course. The goal of the study was to determine ways in which genotype and environmental characteristics influence health and development in both children and parents Note: All published information has been collected from the article referenced in the Marker Paper box below. Therefore, there may be variations with more advanced versions of the study.
Start Year
1991
Funding
Grant support: 92830/Z/10/Z/Wellcome Trust/United Kingdom, 092731/Wellcome Trust/United Kingdom, SP/07 1008/24066/British Heart Foundation/United Kingdom, G0701594/Medical Research Council/United Kingdom, G1001357/Medical Research Council/United Kingdom .
Visit ALSPAC

Members

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Investigators Contacts
  • Andy Boyd
    University of Bristol

Design

Study design
Population cohort
Follow Up
Pregnant women recruited to study (some of whom had two pregnancies or multiple births during the recruitment period), the children arising from the pregnancy, and their partners have been followed up intensively over two decades.

Marker Paper

Fraser A, Macdonald-Wallis C, Tilling K, et al. Cohort Profile: the Avon Longitudinal Study of Parents and Children: ALSPAC mothers cohort. Int J Epidemiol. 2013;42(1):97-110. doi:10.1093/ije/dys066

PUBMED 22507742

Recruitment

Sources of Recruitment
  • Individuals
  • Families

Number of participants

Number of participants
14,541
Number of participants with biosamples

Access

Availability of data and biosamples

Data
Biosamples
Other

Availability of access information

By contacting the study representative

Timeline

Population

The initial ALSPAC sample consists of 14,541 pregnancies. This is the number of pregnancies for which the mother enrolled in the ALSPAC study and had either returned at least one questionnaire or attended a "Children in Focus" clinic by 19/07/99.
Selection Criteria
Newborns
Twins
Countries
  • United Kingdom
Ethnic Origin
Health Status

Recruitment

Sources of recruitment
  • General population
General Population
  • Volunteer enrolment

Number of participants

Number of participants
14,541
Number of participants with biosamples
Data Collection Event
Participant use mobile data collection.
Start Date
1991-04
End Date
1992-12
Data sources
  • Mobile data collection
    • Mobile phone
    • Smartphone
    • Smartphone apps