Individual Study / Alexopoulos et al.;. Am J Geriatr Psychiatry. 2016

Clinical Case Management Versus Case Management With Problem-Solving Therapy in Low-Income, Disabled Elders With Major Depression: A Randomized Clinical Trial

Clinical Case Management Versus Case Management With Problem-Solving Therapy in Low-Income, Disabled Elders With Major Depression: A Randomized Clinical Trial

Initiatives -
To test the hypotheses that (1) clinical case management integrated with problem-solving therapy (CM-PST) is more effective than clinical case management alone (CM) in reducing depressive symptoms of depressed, disabled, impoverished patients and that (2) development of problem-solving skills mediates improvement of depression. Note: All published information has been collected from the article referenced in the Marker Paper box below. Therefore, there may be variations with more advanced versions of the study.
Start Year
2007
End Year
2013
Funding
Supported by grants from the National Institute of Mental Health (R01 MH075900, R01 MH075897, K24 MH074717, P30 MH085943, T32 MH019132) and the Sanchez Foundation (to GSA)

Design

Study design
Clinical trial cohort

Marker Paper

Alexopoulos GS, Raue PJ, McCulloch C, et al. Clinical Case Management versus Case Management with Problem-Solving Therapy in Low-Income, Disabled Elders with Major Depression: A Randomized Clinical Trial. Am J Geriatr Psychiatry. 2016;24(1):50‐59. doi:10.1016/j.jagp.2015.02.007

PUBMED 25794636

Recruitment

Sources of Recruitment
  • Individuals

Number of participants

Number of participants
187
Number of participants with biosamples

Access

Availability of data and biosamples

Data
Biosamples
Other

Timeline

Population

The study screened 187 older persons identified as depressed by social workers providing services as part of home-delivered meals programs
Selection Criteria
Minimum age
60
Maximum age
95
Newborns
Twins
Countries
  • United States of America
Ethnic Origin
Health Status
  • persons identified as depressed

Recruitment

Sources of recruitment
  • General population

Number of participants

Number of participants
185
Number of participants with biosamples
Data Collection Event
This study will compare the effectiveness of case management combined with problem-solving therapy (CM-PST) versus case management (CM) alone for assisting elderly people with depression.
Start Date
2007-05
End Date
2013-07
Data sources
  • Mobile data collection
    • Smartphone apps