Arrhythmia Genetics in The Netherlands
Initiatives
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The AGNES case-control set consists of individuals with a first acute ST-elevation myocardial infarction. AGNES cases have ECG- registered ventricular fibrillation occurring before reperfusion therapy for an acute and first ST-elevation myocardial infarction. AGNES controls are individuals with a first acute ST-elevation myocardial infarction but without ventricular fibrillation. All cases and controls are recruited at seven heart centers in The Netherlands.
- Start Year
- 2008
- Funding
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Visit AGNES
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Design
- Study design
- Case-control
Marker Paper
Bezzina, C., Pazoki, R., Bardai, A. et al. Genome-wide association study identifies a susceptibility locus at 21q21 for ventricular fibrillation in acute myocardial infarction. Nat Genet 42, 688–691 (2010). https://doi.org/10.1038/ng.623
Recruitment
- Sources of Recruitment
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- Individuals
Number of participants
- Number of participants
- 1,433
- Number of participants with biosamples
- Supplementary Information
- Cases are patients with a first ST-elevation myocardial infarction (STEMI). Aged 18 to 80 years. (672 cases, 761 controls)
Access
Availability of data and biosamples
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