Initiative / STROKOG

Stroke and Cognition Consortium

Stroke and Cognition Consortium

Studies 33
STROKOG is a consortium of longitudinal studies of cognitive disorders following stroke, TIA or small vessel disease. Developed under the auspices of VASCOG (Society for the Study of Vascular Cognitive and Behavioural Disorders), it is the first international effort to harmonise work on post-stroke dementia and is being led by CHeBA researchers at UNSW Sydney. STROKOG aims to facilitate a better understanding of the determinants of vascular contributions to cognitive disorders and help improve the diagnosis and treatment of vascular cognitive disorders (VCD).
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Investigators Contacts
  • Prof. Perminder Sachdev
    Centre for Healthy Brain Ageing (CHeBA), UNSW Sydney
  • Jess Lo

General Information

Year created
2015
Types of cohorts
  • Population cohort
  • Patient/disease cohort
  • Clinical trial
Countries
  • South Korea
  • Bulgaria
  • France
  • Netherlands
  • Australia
  • United Kingdom
  • Nigeria
  • Singapore
  • Poland
  • Germany
  • South Africa
  • United States of America
  • Sweden
  • Finland
  • Ireland
  • Hong Kong
  • China
Region
Setting
International
Funding
Vincent Fairfax Family Foundation (VFFF); the National Health and Medical Research Council (Australia)
Criteria of cohort's to be included
1. Prospective in recruitment and evaluation; 2. Have a minimum of 75 participants; 3. Include cognitive outcomes as one of the primary objectives; 4. Are longitudinal, with a minimum of two assessments. All of the cohorts included are longitudinal observation studies with stroke/TIA patient cohorts.
Health topic
  • Mental health
  • Cardiovascular diseases
  • Neurological diseases
Socio-environmental context
  • NA

Participants

Number of participants

Total
16,000
With harmonized data
3,100

Age range of the samples

Minimum age
12
Maximum age
98

Methodology for harmonization and integration

Strategy of harmonization
Ex-post
Data processing methods
  • Algorithmic
  • Standardisation
  • Type of infrastructure
    Some centrally, other locally
    Software
  • Stata
  • SPSS
  • Other
  • Number of cohorts

    Total
    33
    With harmonized data
    14
    Will more cohorts be harmonized?
    Number of harmonized variables (max.)
    60

    Access

    Availability of metadata
    Under request
    Availability of individual data
    Under request

    Individual Studies

    Acronym Name Study design Participants Countries
    Bundand - VCI Bundang VCI cohort Patients' cohort 1,368
    Bylgarian Post-Stroke Study Bylgarian Post-Stroke Study Patients' cohort 85
    CANVAS Cognition and Neocortical Volume After Stroke Study Patients' cohort 135
    CASPER Cognition and Affect after Stroke: Prospective Evaluation of Risks Patients' cohort 250
    COGFAST-UK Cognitive Function After Stroke Patients' cohort 355
    BIOSTROKE Clinical Biological and Pharmacological Factors Influencing Stroke Outcome Patients' cohort 477
    COAST Cognitive Outcome After Stroke Patients' cohort 400
    CogFAST-NIGERIA Cognitive Function After Stroke Study Patients' cohort 143
    CRACOW Cracow Stroke Database Patients' cohort 250
    ASPIRE-S Action on Secondary Prevention Interventions and Rehabilitation in Stroke Study (ASPIRE-S) Patients' cohort 256
    CODAS Maastricht Cognitive Disorders After Stroke Patients' cohort 194
    DEDEMAS Determinants of Dementia After Stroke Patients' cohort 600
    DSDB Durban Stroke Data Bank Patients' cohort 1,000
    EPI USA Epidemiologic Study of the Risk of Dementia After Stroke Patients' cohort 585
    GÖTEBORG NEURO70+ Göteborg 70+ Stroke Study Patients' cohort 249
    GRECog-Vasc Study Groupe de Réflexion pour l'Evaluation COGnitive VASCulaire study Patients' cohort 360
    INSIST-COG Systems of Care in Minor Stroke & TIA: Cognition Patients' cohort 120
    K-VCIHS Multicenter Prospective Stroke Cohort in Korea Patients' cohort 620
    MSS-II Mild Stroke Study II Patients' cohort 264
    NEMESIS North East Melbourne Stroke Incidence Study Patients' cohort 99
    NNI Singapore National Neuroscience Institute Study Patients' cohort 506
    PITCH Prognosis of IntraCerebral Haemorrhage Patients' cohort 562
    PODCAST Prevention Of Decline in Cognition After Stroke Trial Patients' cohort 83
    POSPER Prospective Study of Pravastatin in the Elderly at Risk Patients' cohort 649
    RCCS Renji CSVD Cohort Study Patients' cohort 200
    SAM Helsinki Stroke Aging Memory Patients' cohort 486
    SCANS St George's Cognition and Neuroimaging in Stroke Patients' cohort 121
    SLSR South London Stroke Register Patients' cohort 6,000
    SSS Sydney Stroke Study Patients' cohort 252
    STRIDE Stroke Registry Investigating cognitive Decline Patients' cohort 1,013
    STROKDEM Study of Factors Influencing Post-Stroke Dementia Patients' cohort 195
    The HKU stroke cohort The HKU stroke cohort Patients' cohort 1,000
    The Striategic Study White Matter Connections and Memory: The STRATEGIC Study Patients' cohort 179