Initiative / ReACH

Research Advancement through Cohort Cataloguing and Harmonization

Research Advancement through Cohort Cataloguing and Harmonization

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Studies 0
The aim of ReACH is to provide resources in the form of a comprehensive web-based catalogue and an harmonization platform to optimize and expand the use of Canadian pregnancy and birth cohorts data and biological samples.
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Members

Investigators Contacts
  • Dr. Isabel Fortier
    Research Institute of the McGill University Health Centre

General Information

Year created
2016
Types of cohorts
  • Population cohort
  • Patient/disease cohort
  • Clinical trial
Countries
  • Argentina
  • Australia
  • Belgium
  • Brazil
  • Canada
  • Chile
  • Croatia
  • Egypt
  • Estonia
  • Germany
  • Greece
  • Hungary
Region
Principally Canada
Setting
International
Funding
This project has received funding from the CIHR Operating Grant for the Canadian DoHaD Cohort Registry
Criteria of cohort's to be included
(1) recruit Canadian mothers and/or children; (2) have a longitudinal design (i.e. at least one follow-up of participants after the initial collection event); (3) have collected data (baseline or follow-up) after 2000; (4) collect information on pregnancy and birth outcomes
Socio-environmental context
  • NA

Participants

Number of participants

Total
89,889

Age range of the samples

Minimum age
0
Maximum age
45

Methodology for harmonization and integration

Strategy of harmonization
Ex-post
Data processing methods
  • Algorithmic
  • Calibration
  • Standardisation
  • Latent variable model
  • Multiple imputation
  • Others
  • Type of infrastructure
    Some centrally, other locally
    Integrative data analysis
    • Pooled analyses
    Software
  • OBiBa (Opal/Mica)
  • R / Rmarkdown
  • Other
  • Supplementary information
    The harmonisation will be achieved to serve the needs of a series of case studies. The strategies of harmonization are in some cohorts prospective and another retrospective.

    Number of cohorts

    Will more cohorts be harmonized?

    Access

    Availability of metadata
    Availability of individual data
    Under request