Initiative / InterLACE

International Collaboration for a Life Course Approach to Reproductive Health and Chronic Disease Events

International Collaboration for a Life Course Approach to Reproductive Health and Chronic Disease Events

InterLACE logo
Studies 17
The aim of InterLACE is to advance understandingof women’s reproductive health in relation to chronic disease risk by pooling individual participant data from several cohort and cross-sectional studies.
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Investigators Contacts
  • Prof. Gita Mishra
    The University of Queensland School of Public Health

General Information

Year created
Types of cohorts
  • Population cohort
  • Australia
  • United Kingdom
  • Denmark
  • France
  • Japan
  • United States of America
  • Lebanon
  • Spain
  • Sweden
  • Morocco
  • China
This project has received funding from the National Health and Medical Research Council (NHMRC) and the Australian Research Council (ARC).
Criteria of cohort's to be included
Observational studies, which had collected prospective or retrospective survey data on women’s reproductive health across the lifespan (such as ages at menarche, first birth, and natural menopause), sociodemographic and lifestyle factors, and chronic disease events, could contribute data to the InterLACE consortium, regardless of the sample size and ethnic background of participants.
Health topic
  • Reproductive health
  • Chronic diseases
Socio-environmental context
  • NA


Number of participants

With harmonized data

Age range of the samples

Minimum age
Maximum age

Methodology for harmonization and integration

Strategy of harmonization
Data processing methods
  • NA
  • Type of infrastructure
    Data are centrally located
    Integrative data analysis
    • Pooled analyses
  • SAS
  • Supplementary information
    Mishra G et al. The InterLACE study: Design, data harmonization and characteristicsacross 20 studies on women’s health. Maturitas 92 (2016) 176–185. doi:10.1016/j.maturitas.2016.07.021

    Number of cohorts

    With harmonized data
    Will more cohorts be harmonized?
    Number of harmonized variables (max.)


    Availability of metadata
    Availability of individual data

    Individual Studies

    Acronym Name Study design Participants Countries
    ALSWH Australian Longitudinal Study on Women’s Health Population cohort 41,638
    AJMWHS Australian and Japanese Midlife Women’s Health Study Population cohort 1,743
    DNC Danish Nurse Cohort Study Population cohort 19,898
    MCCS Melbourne Collaborative Cohort Study (or Health 2020) Population cohort 41,513
    3C Study French Three-City Study Population cohort 9,294
    BCS70 The 1970 British Cohort Study Population cohort 17,196
    DAMES Decisions At Menopause Study Population cohort 1,190
    ELSA English Longitudinal Study of Ageing Population cohort 12,099 United Kingdom
    HILO Hilo Women’s Health Study Population cohort 508
    MRC-NSHD The Medical Research Council (MRC) National Survey of Health and Development (NSHD) Population cohort 5,362
    NCDS National Child Development Study Population cohort 17,634
    SFMWHS San Francisco Midlife Women’s Health Study Population cohort 346
    SMWHS Seattle Midlife Women’s Health Study Population cohort 508
    SWAN Study of Women’s Health Across the Nation Population cohort 3,302
    WLH Swedish Women’s Lifestyle and Health Study Population cohort 49,259
    UK Biobank UK Biobank Population cohort 502,543
    UKWCS UK Women’s Cohort Study Population cohort 32,784