Initiative / IHCC

International HundredK+ Cohorts Consortium

International HundredK+ Cohorts Consortium

IHCC logo
Studies 61
To create a global network for translational research that utilizes large cohorts to enhance the understanding of the biological and genetic basis of disease and improve clinical care and population health. They also put in common challenges and better strategies in sharing data across cohorts.
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Investigators Contacts
  • Dr. Geoffrey Ginsburg
    The Global Genomic Medicine Collaborative (G2MC)

General Information

Year created
Types of cohorts
  • Population cohort
Global Genomics Medicine Collaborative
Criteria of cohort's to be included
Cohorts that recruit 100k participants or more, are disease-agnostic, have available biospecimens, and have longitudinal follow-up activities. Cohorts from under-represented populations and low and middle-income countries (LMICs) may not fit some of these criteria, so exceptions are made to be inclusive as possible.
Health topic
  • Public health
  • Genetics
Socio-environmental context
  • NA


Number of participants

Age range of the samples

Minimum age
Maximum age

Methodology for harmonization and integration

Strategy of harmonization
Data processing methods
  • NA
  • Type of infrastructure
    Data are in different locations
    Integrative data analysis
    • Federated analyses
  • NA
  • Number of cohorts

    With harmonized data
    Will more cohorts be harmonized?


    Availability of metadata
    Availability of individual data

    Individual Studies

    Acronym Name Study design Participants Countries
    23andMe 23andMe Population cohort 2,000,000
    45 and Up Study 45 and Up Study Population cohort 267,153
    AHRI HDSS Africa Health Research Institute (AHRI) Population Cohort Population cohort 168,000
    All of Us All of Us Research Program Population cohort 175,000
    BBJ Biobank Japan Patients' cohort 200,000
    BioVU BioVU Vanderbilt Population cohort 240,000
    Cancer Prevention Study II Nutrition Cohort Cancer Prevention Study II Nutrition Cohort Population cohort 184,194
    CanPath CanPath – the Canadian Partnership for Tomorrow’s Health Population cohort 331,359
    Children's Hospital of Philadelphia (CHOP) Biorepository Children's Hospital of Philadelphia (CHOP) Biorepository Patients' cohort 500,000
    China PEACE Patient-Centered Evaluative Assessment of Cardiac Events Population cohort 400,000
    CKB China Kadoorie Biobank Population cohort 512,891
    CONSTANCES Cohorte des consultants des Centres d’examens de santé Population cohort 200,000
    CPS-II The American Cancer Society Cancer Prevention Study II Population cohort 181,000
    DNBC Danish National Birth Cohort Population cohort 101,042
    EFRCV-MURCIA Estudio de Factores de Riesgo Cardiovascular Population cohort 3,091
    ELGH East London Genes and Health Population cohort 30,000
    ELSA Brasil The Longitudinal Study of Adult Health Population cohort 15,105
    EPIC European Prospective Investigation into Cancer, Chronic Diseases, Nutrition and Lifestyle Patients' cohort 522,000
    EpiHealth EpiHealth Population cohort 24,000
    FMC Finnish Maternity Cohort Serum Bank Population cohort 2,000,000
    Golestan Cohort Study Golestan Cohort Study Population cohort 50,045
    GS Generations Study Population cohort 112,049
    Healthy NV Project Healthy Nevada Project Population cohort 52,512
    JPHC Japan Public Health Center-based Prospective Study Population cohort 140,420
    JPHC-NEXT Japan Public Health Center-based Prospective Study for the Next Generation Population cohort 115,385
    KBP Korea Biobank Project Population cohort 929,405
    KCPS-II Korean Cancer Prevention Study Population cohort 156,701
    LifeGene LifeGene (and sister cohort, EpiHealth) Population cohort 52,107
    LIFEPATH Lifecourse biological pathways underlying social differences in healthy aging Population cohort 235,000
    MCPS Mexico City Prospective Study Population cohort 150,000
    MEC Multiethnic Cohort Study Population cohort 215,251
    MoBa Norwegian Mother and Child Cohort Study Population cohort 285,200
    MVP Million Veteran Program, USA Patients' cohort 825,000
    MWS Million Women Study, England, Scotland Population cohort 700,000
    MyCode MyCode Community Health Initiative Population cohort 250,000
    NFLC Norwegian Family Based Life Course Study Population cohort 5,266,270
    NHS Nurses' Health Study Population cohort 121,700
    NHS-II Nurses' Health Study II Population cohort 116,430
    NICCC Clalit National Israeli Cancer Control Center Population cohort 40,000
    NL Genome Project Newfoundland & Labrador (Canada) genome project / Sequence Bio Population cohort 2,500
    NSHDS Northern Sweden Health and Disease Study Population cohort 135,000
    VUNTR Netherlands Twin Registry Population cohort 60,000
    OPENGENE Estonian Genome Project Population cohort 200,000
    PERSIAN Cohort Study Prospective Epidemiological Research Studies Iran Population cohort 170,000
    PGR Pakistan Genomic Resource Population cohort 150,000
    PLCO Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial Clinical trial 155,000
    QGP Qatar Genome Project Population cohort 19,000
    RPGEH Kaiser Permanente Research Program on Genes, Environment, and Health Population cohort 100,000
    SAPRIN South African Population Research Infrastructure Network Population cohort 341,000
    SHGP Saudi Human Genome Program Population cohort 20,000
    SMHS The Shanghai Men’s Health Study Population cohort 61,582
    SWHS Shanghai Women's Health Study Population cohort 75,000
    The 100,000 Genomes Project The 100,000 Genomes Project Patients' cohort 97,000
    The INTERVAL study UK Blood Donor Cohorts (INTERVAL & COMPARE) Population cohort 45,263
    MAUCO The Maule Cohort Population cohort 10,000
    TMC The Malaysian Cohort Population cohort 130,000
    TWB Taiwan Biobank Patients' cohort 140,000
    UK Biobank UK Biobank Population cohort 502,543
    UKLWC UK Collaborative Trial of Ovarian Cancer Screening - Longitudinal Women’s Cohort Population cohort 202,280
    VHM&PP Vorarlberg Health Monitoring and Promotion Programme Population cohort 180,000
    WHI Women's Health Initiative Other 161,000